Group B streptococcal infection
小结
定义
病史和体格检查
关键诊断因素
- fever
- symptoms of meningitis
- signs of meningitis
- symptoms of sepsis
- signs of sepsis
- symptoms of pneumonia
- signs of pneumonia
- symptoms of urinary tract infection
- signs of urinary tract infection
- symptoms of cellulitis
- signs of cellulitis
- symptoms of septic arthritis
- signs of septic arthritis
- symptoms of conjunctivitis
- symptoms of sinusitis
- signs of sinusitis
- symptoms of otitis media
- signs of otitis media
- symptoms of endometritis
- signs of endometritis
- signs of chorioamnionitis
其他诊断因素
- nonspecific signs of infection in neonate
- nonspecific signs of infection in older patients
- symptoms of intra-abdominal infection
- signs of intra-abdominal infection
- midgestation abortion or preterm labor
危险因素
- 0 to 7 days of age
- maternal fever during labor
- premature rupture of membranes (PROM)
- previous baby with GBS disease
- maternal GBS colonization
- GBS bacteriuria during pregnancy
- preterm delivery (<37 weeks)
- low birth weight (<2500 g)
- deficient maternal-specific IgG at term
- twin sibling with GBS disease
- maternal age <20 years
- chorioamnionitis
- age >60 years
- pregnancy
- multiparity
- diabetes
- obesity
- advanced hepatic disease
- renal disease
- presence of central venous catheter
- urologic disorders
- break in skin integrity or skin ulcers
- neurologic disease
- immunosuppression
- nursing-home resident
- black or Hispanic race
- malignancy
- obstetric manipulation
- presence of urinary catheter
- HIV infection
- trauma
- asthma
- consumption of placenta capsules
诊断性检查
首要检查
- CBC
- BUN
- serum electrolytes
- serum glucose
- coagulation studies
- LFTs
- C-reactive protein (CRP)
- blood culture
- cerebrospinal fluid (CSF) Gram stain
- CSF culture
- CSF cell count and differential
- CSF glucose and protein
- antigen detection in CSF
- Gram stain and culture of other sterile body fluids
- chest x-ray
- plain joint and/or bone x-ray
- CT head
需考虑的检查
- echocardiography
- MRI
治疗流程
early- or late-onset confirmed GBS neonatal infection (0-89 days of age)
infants and children
adults: nonpregnant
adults: pregnant and postpartum
撰稿人
作者
Brendan Healy, MBChB, BSc (Hons), MRCP, FRCPath
Consultant in Microbiology and Infectious Diseases
University Hospital of Wales
Cardiff
UK
利益声明
BH has received honorarium and has been reimbursed for attending conferences from AbbVie (hepatitis C), Gilead Sciences (hepatitis C), Bristol Myers Squibb (hepatitis C), and Tillotts Pharma (fidaxomicin). BH declares that he has no competing interests in relation to the work carried out for this topic review, Group B streptococcus.
鸣谢
Dr Brendan Healy would like to gratefully acknowledge Dr Susannah Froude and Dr Harriet Hughes, previous contributors to this topic. We would also like to gratefully acknowledge Dr Benjamin D. Lorenz for his contributions to this topic.
利益声明
SF declares that she has no competing interests. HH declares that she has received funds from Gilead and Biocomposites related to conference registration, travel, accommodation, and speaker fees.
同行评议者
William A. Petri, Jr, MD, PhD, FACP
Chief and Professor of Medicine
Division of Infectious Diseases and International Health
University of Virginia Health System
Charlottesville
VA
利益声明
WAP declares that he has no competing interests.
James R. Hanley, MD, FAAP
Attending Physician
Pediatric Emergency Medicine
Ochsner Foundation Hospital
New Orleans
LA
გაფრთხილება:
JRH declares that he has ownership of a limited amount of stock in various pharmaceutical companies, although no significant amounts of any company.
Kirsty Le Doare, BA, MBBS, MSc, PhD, FRCPCH
Professor of Vaccinology and Immunology
St George's, University of London
London
UK
გაფრთხილება:
KLD declares that their institution has received funds for GBS vaccine clinical trials; she has not received personal funds.
რეცენზენტების განცხადებები
BMJ Best Practice-ის თემების განახლება სხვადასხვა პერიოდულობით ხდება მტკიცებულებებისა და რეკომენდაციების განვითარების შესაბამისად. ქვემოთ ჩამოთვლილმა რეცენზენტებმა თემის არსებობის მანძილზე კონტენტს ერთხელ მაინც გადახედეს.
გაფრთხილება
რეცენზენტების აფილიაციები და გაფრთხილებები მოცემულია გადახედვის მომენტისთვის.
წყაროები
ძირითადი სტატიები
American Academy of Pediatrics. Group B streptococcal infections. In: Committee on Infectious Diseases, American Academy of Pediatrics, Kimberlin DW, Barnett ED, et al. Red book: 2021-2024 report of the Committee on Infectious Diseases. 32nd ed. Elk Grove Village, IL: AAP; 2021:707-13.
The American College of Obstetricians and Gynecologists. Prevention of group B streptococcal early-onset disease in newborns: ACOG Committee Opinion Summary, Number 797. Obstet Gynecol. 2020 Feb;135(2):489-92.სრული ტექსტი აბსტრაქტი
National Center for Health Statistics. Active bacterial core surveillance (ABCs) report: emerging infections program network - group B streptococcus, 2018 [internet publication].სრული ტექსტი
Royal College of Obstetricians and Gynaecologists. The prevention of early onset neonatal group B streptococcal disease. Green-top guideline no. 36. Sep 2017 [internet publication].სრული ტექსტი აბსტრაქტი
Ohlsson A, Shah VS. Intrapartum antibiotics for known maternal Group B streptococcal colonization. Cochrane Database Syst Rev. 2014 Jun 10;(6):CD007467.სრული ტექსტი აბსტრაქტი
Puopolo KM, Lynfield R, Cummings JJ, et al. Management of infants at risk for group B streptococcal disease. Pediatrics. 2019 Aug;144(2):e20191881.სრული ტექსტი აბსტრაქტი
American Society for Microbiology. Guidelines for the detection and identification of group B streptococcus. 29 July 2021 [internet publication].სრული ტექსტი
გამოყენებული სტატიები
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დიფერენციული დიაგნოზები
- Sepsis caused by other organisms
- Endocarditis caused by other organisms
- Neonatal cytomegalovirus (CMV) infection
მეტი დიფერენციული დიაგნოზებიგაიდლაინები
- Guidelines for the detection and identification of group B streptococcus
- Prevention of early-onset group B streptococcal disease in newborns
მეტი გაიდლაინებიპაციენტის ბროშურები
Cellulitis and erysipelas
Conjunctivitis
მეტი პაციენტის ბროშურები
შედით სისტემაში ან გამოიწერეთ BMJ Best Practice
ამ მასალის გამოყენება ექვემდებარება ჩვენს განცხადებას