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Group B streptococcal infection

ბოლო მიმოხილვა: 12 Dec 2025
ბოლო განახლება: 11 Oct 2024

შეჯამება

განსაზღვრება

ანამნეზი და გასინჯვა

ძირითადი დიაგნოსტიკური ფაქტორები

  • fever
  • symptoms of meningitis
  • signs of meningitis
  • symptoms of sepsis
  • signs of sepsis
  • symptoms of pneumonia
  • signs of pneumonia
  • symptoms of urinary tract infection
  • signs of urinary tract infection
  • symptoms of cellulitis
  • signs of cellulitis
  • symptoms of septic arthritis
  • signs of septic arthritis
  • symptoms of conjunctivitis
  • symptoms of sinusitis
  • signs of sinusitis
  • symptoms of otitis media
  • signs of otitis media
  • symptoms of endometritis
  • signs of endometritis
  • signs of chorioamnionitis
სრული ტექსტი

სხვა დიაგნოსტიკური ფაქტორები

  • nonspecific signs of infection in neonate
  • nonspecific signs of infection in older patients
  • symptoms of intra-abdominal infection
  • signs of intra-abdominal infection
  • midgestation abortion or preterm labor
სრული ტექსტი

რისკფაქტორები

  • 0 to 7 days of age
  • maternal fever during labor
  • premature rupture of membranes (PROM)
  • previous baby with GBS disease
  • maternal GBS colonization
  • GBS bacteriuria during pregnancy
  • preterm delivery (<37 weeks)
  • low birth weight (<2500 g)
  • deficient maternal-specific IgG at term
  • twin sibling with GBS disease
  • maternal age <20 years
  • chorioamnionitis
  • age >60 years
  • pregnancy
  • multiparity
  • diabetes
  • obesity
  • advanced hepatic disease
  • renal disease
  • presence of central venous catheter
  • urologic disorders
  • break in skin integrity or skin ulcers
  • neurologic disease
  • immunosuppression
  • nursing-home resident
  • black or Hispanic race
  • malignancy
  • obstetric manipulation
  • presence of urinary catheter
  • HIV infection
  • trauma
  • asthma
  • consumption of placenta capsules
სრული ტექსტი

დიაგნოსტიკური კვლევები

1-ად შესაკვეთი გამოკვლევები

  • CBC
  • BUN
  • serum electrolytes
  • serum glucose
  • coagulation studies
  • LFTs
  • C-reactive protein (CRP)
  • blood culture
  • cerebrospinal fluid (CSF) Gram stain
  • CSF culture
  • CSF cell count and differential
  • CSF glucose and protein
  • antigen detection in CSF
  • Gram stain and culture of other sterile body fluids
  • chest x-ray
  • plain joint and/or bone x-ray
  • CT head
სრული ტექსტი

გასათვალისწინებელი კვლევები

  • echocardiography
  • MRI
სრული ტექსტი

მკურნალობის ალგორითმი

მწვავე

early- or late-onset confirmed GBS neonatal infection (0-89 days of age)

infants and children

adults: nonpregnant

adults: pregnant and postpartum

კონტრიბუტორები

ავტორები

Brendan Healy, MBChB, BSc (Hons), MRCP, FRCPath

Consultant in Microbiology and Infectious Diseases

University Hospital of Wales

Cardiff

UK

გაფრთხილება:

BH has received honorarium and has been reimbursed for attending conferences from AbbVie (hepatitis C), Gilead Sciences (hepatitis C), Bristol Myers Squibb (hepatitis C), and Tillotts Pharma (fidaxomicin). BH declares that he has no competing interests in relation to the work carried out for this topic review, Group B streptococcus.

მადლიერება

Dr Brendan Healy would like to gratefully acknowledge Dr Susannah Froude and Dr Harriet Hughes, previous contributors to this topic. We would also like to gratefully acknowledge Dr Benjamin D. Lorenz for his contributions to this topic.

გაფრთხილება:

SF declares that she has no competing interests. HH declares that she has received funds from Gilead and Biocomposites related to conference registration, travel, accommodation, and speaker fees.

რეცენზენტები

William A. Petri, Jr, MD, PhD, FACP

Chief and Professor of Medicine

Division of Infectious Diseases and International Health

University of Virginia Health System

Charlottesville

VA

გაფრთხილება:

WAP declares that he has no competing interests.

James R. Hanley, MD, FAAP

Attending Physician

Pediatric Emergency Medicine

Ochsner Foundation Hospital

New Orleans

LA

Divulgaciones

JRH declares that he has ownership of a limited amount of stock in various pharmaceutical companies, although no significant amounts of any company.

Kirsty Le Doare, BA, MBBS, MSc, PhD, FRCPCH

Professor of Vaccinology and Immunology

St George's, University of London

London

UK

Divulgaciones

KLD declares that their institution has received funds for GBS vaccine clinical trials; she has not received personal funds.

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Referencias

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Artículos principales

American Academy of Pediatrics. Group B streptococcal infections. In: Committee on Infectious Diseases, American Academy of Pediatrics, Kimberlin DW, Barnett ED, et al. Red book: 2021-2024 report of the Committee on Infectious Diseases. 32nd ed. Elk Grove Village, IL: AAP; 2021:707-13.

The American College of Obstetricians and Gynecologists. Prevention of group B streptococcal early-onset disease in newborns: ACOG Committee Opinion Summary, Number 797. Obstet Gynecol. 2020 Feb;135(2):489-92.Texto completo  Resumen

National Center for Health Statistics. Active bacterial core surveillance (ABCs) report: emerging infections program network - group B streptococcus, 2018 [internet publication].Texto completo

Royal College of Obstetricians and Gynaecologists. The prevention of early onset neonatal group B streptococcal disease. Green-top guideline no. 36. Sep 2017 [internet publication].Texto completo  Resumen

Ohlsson A, Shah VS. Intrapartum antibiotics for known maternal Group B streptococcal colonization. Cochrane Database Syst Rev. 2014 Jun 10;(6):CD007467.Texto completo  Resumen

Puopolo KM, Lynfield R, Cummings JJ, et al. Management of infants at risk for group B streptococcal disease. Pediatrics. 2019 Aug;144(2):e20191881.Texto completo  Resumen

American Society for Microbiology. Guidelines for the detection and identification of group B streptococcus. 29 July 2021 [internet publication].Texto completo

Artículos de referencia

Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
  • Group B streptococcal infection images
  • Diferenciales

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    • Endocarditis caused by other organisms
    • Neonatal cytomegalovirus (CMV) infection
    Más Diferenciales
  • Guías de práctica clínica

    • Guidelines for the detection and identification of group B streptococcus
    • Prevention of early-onset group B streptococcal disease in newborns
    Más Guías de práctica clínica
  • Folletos para el paciente

    Cellulitis and erysipelas

    Conjunctivitis

    Más Folletos para el paciente
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