Last reviewed:September 2019
Last updated:November  2018

Summary

Definition

History and exam

Key diagnostic factors

  • exposure to infected birds and mammals
  • illness in other family members

Other diagnostic factors

  • fever
  • malaise
  • headache
  • cough
  • sore throat
  • rales
  • tachypnea
  • pharyngitis
  • conjunctivitis
  • hepatomegaly
  • confusion
  • tachycardia
  • splenomegaly

Risk factors

  • exposure to infected birds and mammals
  • young children
  • older adults
  • immunocompromised

Diagnostic investigations

1st investigations to order

  • white blood cell count with differential
  • liver function tests
  • polymerase chain reaction (PCR)
  • chest x-ray
Full details

Treatment algorithm

Contributors

Deborah Dean

Director

Children’s Global Health Initiative

Senior Scientist

Center for Immunobiology and Vaccine Development

Professor of Medicine

University of California at San Francisco and Berkeley

Faculty, the UC Berkeley - UCSF Graduate Program in Bioengineering

Children's Hospital Oakland Research Institute

Oakland

CA

Disclosures

DD declares that she has no competing interests.

Peer reviewersVIEW ALL

Head of Laboratory of Immunogenetics

VU University Medical Center

Department of Pathology

Laboratory of Immunogenetics

Amsterdam

Netherlands

Disclosures

SM declares that he has no competing interests.

Chief and Professor of Medicine

Division of Infectious Diseases and International Health

University of Virginia Health System

Charlottesville

VA

Disclosures

WAP declares that he has no competing interests.

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