Severe acute respiratory syndrome (SARS)
Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- history of travel to affected area
- history of close contact with infected individuals
- history of laboratory work on SARS-CoV
- fever
- cough
- myalgia
- dyspnea
Outros fatores diagnósticos
- chills or rigors
- malaise
- headache
- watery diarrhea
- tachypnea
- tachycardia
- cyanosis
- nausea and vomiting
- sore throat
- sputum production
- chest pain
- pleurisy
- rhinorrhea
- dizziness
- arthralgia
- abdominal pain
- seizure
- delirium
- rales
- inspiratory crackles
- bronchial breathing
Fatores de risco
- travel to affected area
- close contact with infected individuals
- laboratory work on SARS-CoV
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- CBC
- aminotransferases
- lactate dehydrogenase
- creatine kinase
- blood culture
- sputum culture
- nasopharyngeal virus culture
- direct immunofluorescent antibody staining
- chest x-ray
- pulse oximetry
- reverse-transcription polymerase chain reaction (RT-PCR)
Investigações a serem consideradas
- ABG
- coagulation screen
- high-resolution CT (HRCT) of thorax
- serologic testing for SARS-CoV-specific antibodies
- viral culture
Novos exames
- rapid immunoswab assay for SARS-CoV detection
- monoclonal antibodies
Algoritmo de tratamento
suspected SARS
confirmed SARS
Colaboradores
Autores
Georgia G. Pitsiou, MD, PhD
Associate Professor in Pulmonary Medicine
Aristotle University of Thessaloniki
Respiratory Failure Clinic
General Hospital G. Papanikolaou
Thessaloniki
Greece
Declarações
GGP declares that she has no competing interests.
Ioannis P. Kioumis, MD, PhD
Professor in Pulmonary Medicine
Infectious Diseases
Aristotle University of Thessaloniki
Respiratory Failure Clinic
General Hospital G. Papanikolaou
Thessaloniki
Greece
Раскрытие информации
IPK declares that he has no competing interests.
Рецензенты
Tommy R. Tong, MD
Attending Pathologist
Montefiore Medical Center
Bronx
NY
Раскрытие информации
TRT declares that he has no competing interests.
Sian Griffiths, OBE, MA, MB BChir, FFPHM, FRCP (Lon), FRCP (Edin), FHKCCM
Director of the School of Public Health
Chinese University of Hong Kong
Prince of Wales Hospital
New Territories
Hong Kong
Раскрытие информации
SG declares that she has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Список литературы
Основные статьи
Christian MD, Poutanen SM, Loutfy MR, et al. Severe acute respiratory syndrome. Clin Infect Dis. 2004;38:1420-1427.Полный текст Аннотация
Peiris JS, Chu CM, Cheng VC, et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767-1772. Аннотация
Mahony JB, Richardson S. Molecular diagnosis of severe acute respiratory syndrome: the state of the art. J Mol Diagn. 2005;7:551-559. Аннотация
Peiris JS, Yuen KY, Osterhaus AD, et al. The severe acute respiratory syndrome. N Engl J Med. 2003;349:2431-2441. Аннотация
Fowler RA, Lapinsky SE, Hallet D, et al. Critically ill patients with severe acute respiratory syndrome. JAMA. 2003;290:367-373.Полный текст Аннотация
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Coronavirus disease 2019 (COVID-19)
- Middle East respiratory syndrome (MERS)
- Community-acquired pneumonia
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