When viewing this topic in a different language, you may notice some differences in the way the content is structured, but it still reflects the latest evidence-based guidance.

Severe acute respiratory syndrome (SARS)

  • Overview
  • Theory
  • Diagnosis
  • Management
  • Follow up
  • Resources
Last reviewed: 17 Oct 2025
Last updated: 10 Feb 2022

Summary

定义

病史和体格检查

关键诊断因素

  • history of travel to affected area
  • history of close contact with infected individuals
  • history of laboratory work on SARS-CoV
  • fever
  • cough
  • myalgia
  • dyspnea
完整详情

其他诊断因素

  • chills or rigors
  • malaise
  • headache
  • watery diarrhea
  • tachypnea
  • tachycardia
  • cyanosis
  • nausea and vomiting
  • sore throat
  • sputum production
  • chest pain
  • pleurisy
  • rhinorrhea
  • dizziness
  • arthralgia
  • abdominal pain
  • seizure
  • delirium
  • rales
  • inspiratory crackles
  • bronchial breathing
完整详情

危险因素

  • travel to affected area
  • close contact with infected individuals
  • laboratory work on SARS-CoV
完整详情

诊断性检查

首要检查

  • CBC
  • aminotransferases
  • lactate dehydrogenase
  • creatine kinase
  • blood culture
  • sputum culture
  • nasopharyngeal virus culture
  • direct immunofluorescent antibody staining
  • chest x-ray
  • pulse oximetry
  • reverse-transcription polymerase chain reaction (RT-PCR)
完整详情

需考虑的检查

  • ABG
  • coagulation screen
  • high-resolution CT (HRCT) of thorax
  • serologic testing for SARS-CoV-specific antibodies
  • viral culture
完整详情

新兴检查

  • rapid immunoswab assay for SARS-CoV detection
  • monoclonal antibodies

治疗流程

初步治疗

suspected SARS

急症处理

confirmed SARS

撰稿人

作者

Georgia G. Pitsiou, MD, PhD
Georgia G. Pitsiou

Associate Professor in Pulmonary Medicine

Aristotle University of Thessaloniki

Respiratory Failure Clinic

General Hospital G. Papanikolaou

Thessaloniki

Greece

利益声明

GGP declares that she has no competing interests.

Ioannis P. Kioumis, MD, PhD
Ioannis P. Kioumis

Professor in Pulmonary Medicine

Infectious Diseases

Aristotle University of Thessaloniki

Respiratory Failure Clinic

General Hospital G. Papanikolaou

Thessaloniki

Greece

利益声明

IPK declares that he has no competing interests.

同行评议者

Tommy R. Tong, MD

Attending Pathologist

Montefiore Medical Center

Bronx

NY

利益声明

TRT declares that he has no competing interests.

Sian Griffiths, OBE, MA, MB BChir, FFPHM, FRCP (Lon), FRCP (Edin), FHKCCM

Director of the School of Public Health

Chinese University of Hong Kong

Prince of Wales Hospital

New Territories

Hong Kong

利益声明

SG declares that she has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Christian MD, Poutanen SM, Loutfy MR, et al. Severe acute respiratory syndrome. Clin Infect Dis. 2004;38:1420-1427.全文  摘要

Peiris JS, Chu CM, Cheng VC, et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767-1772. 摘要

Mahony JB, Richardson S. Molecular diagnosis of severe acute respiratory syndrome: the state of the art. J Mol Diagn. 2005;7:551-559. 摘要

Peiris JS, Yuen KY, Osterhaus AD, et al. The severe acute respiratory syndrome. N Engl J Med. 2003;349:2431-2441. 摘要

Fowler RA, Lapinsky SE, Hallet D, et al. Critically ill patients with severe acute respiratory syndrome. JAMA. 2003;290:367-373.全文  摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Severe acute respiratory syndrome (SARS) images

  • Differentials

    • Coronavirus disease 2019 (COVID-19)
    • Middle East respiratory syndrome (MERS)
    • Community-acquired pneumonia
    更多 鉴别诊断

  • Guidelines

    • Severe acute respiratory syndrome (SARS)
    • No. 225-Management guidelines for obstetric patients and neonates born to mothers with suspected or probable severe acute respiratory syndrome (SARS)
    更多 Guidelines

  • Patient information

    Pneumonia

    More Patient information

  • Videos

    Radial artery puncture animated demonstration

    Femoral artery puncture animated demonstration

    More videos
  • padlock-lockedLog in or subscribe to access all of BMJ Best Practice

Use of this content is subject to our disclaimer