Falls are often multifactorial in origin.  The presence of the following factors is associated with greater probability of future falls,   and falls screening guidelines suggest identification of these characteristics in at-risk people can be useful in the implementation of falls prevention strategies:
Polypharmacy or certain medications (particularly psychotropic medications) 
Impairment of activities of daily living 
Environmental hazards (e.g., loose rugs, poor lighting, clutter) 
Additional factors such as age or comorbid illnesses. 
Key components of many fall-prevention programs include addressing the risk factors, advocating exercise (including strength and balance training), review of medications taken, vision assessment, and a home safety assessment, with modifications as deemed necessary.  The United States Preventive Services Task Force, for example, recommends exercise (e.g., group exercise, tai chi, multicomponent exercises) or physical therapy for prevention of falls in community-dwelling adults ≥65 years of age who are at increased risk of falls.   Meta-analyses of vitamin D supplementation (alone or with calcium) has not shown benefit in terms of reduction of falls. 
One Cochrane systematic review found that multiple component interventions (that offer the same component interventions to all people without taking into account any assessment of risk of falls; most of which include exercise) may reduce the number of falls and the risk of falling compared with usual care or attention control in older people living in the community. It also found that multifactorial interventions (component interventions that differ between people depending on their assessment of risk of falls) may reduce falls in older people in the community compared with usual care or attention control.  [ ]
One network meta-analysis found the following interventions were more effective than usual care at preventing falls that result in injuries: 
Combined exercise, vision assessment and treatment
Combined exercise, vision assessment and treatment, environmental assessment and modification
Combined clinic-level quality-improvement strategies (e.g., case management), multifactorial assessment and treatment, calcium and vitamin D supplementation.
Several guidelines have examined the implementation of such interventions to prevent falls:
Falls are the leading cause of death due to unintentional injury in people ages 65 and older in the US.  One in four older adults report falling at least once yearly, leading to approximately 3 million emergency department visits. Data collected from 2007 to 2016 demonstrate that this rate has been increasing by approximately 3% per year.  Almost all age and demographic categories experienced an increase, but the greatest increase was noted in individuals ages 85 and older. The death rate from falls was also higher in this age group. 
Identifying the circumstances surrounding, and the symptoms associated with, a fall helps to determine the underlying cause, which in turn emphasizes the importance of obtaining a detailed history of the fall. Identifying the cause will determine whether a more urgent medical evaluation is necessary to address life-threatening causes of falls and their consequences. This investigation will also help to identify the risk factor(s) most likely to be contributing to falls and allow the implementation of appropriate interventions to reduce the risk of future falls.
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Geriatric Medicine Fellowship Program Director
Center for Geriatric Medicine, Medicine Institute
RF is a Pfizer stockholder.
Professor of Medicine
Division of Geriatric Medicine
Saint Louis University
DT declares that he has no competing interests.
Nuffield Department of Medicine
John Radcliffe Hospital
AD declares that he has no competing interests.
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