Last reviewed:December 2019
Last updated:January  2020

Summary

Definition

History and exam

Key diagnostic factors

  • right upper quadrant abdominal pain
  • hepatomegaly
  • ascites
  • jaundice

Other diagnostic factors

  • splenomegaly
  • gastrointestinal bleeding
  • leg edema
  • truncal venous collaterals
  • hepatic encephalopathy

Risk factors

  • female sex
  • myeloproliferative disorders (MPD)
  • thrombophilic disorders
  • oral contraceptive pill use
  • pregnancy and immediate postpartum period

Diagnostic investigations

Treatment algorithm

Contributors

Soha Saoud Abdel Moneim

Lecturer of Gastroenterology and Hepatology

Assiut University

Assiut

Egypt

Disclosures

SSAM declares that she has no competing interests.

Vijay H. Shah

Professor of Medicine

Physiology and Cancer Cell Biology

Mayo Clinic

Rochester

MN

Disclosures

VHS is the author of studies referenced in this topic. VHS is on the advisory boards of the following companies: Novartis Pharmaceuticals, Merck and Company, Enterome Corporation, Durect Corporation, Afimmune Ltd., Vital Therapies.

Peer reviewersVIEW ALL

Professor of Medicine and Cell Biology

Columbia University College of Physicians and Surgeons

New York

NY

Disclosures

HJW declares that he has no competing interests.

Senior Lecturer in Hepatology & Honorary Consultant Physician

Liver Research Group

Institute of Biomedical Research

The Medical School

University of Birmingham

Birmingham

UK

Disclosures

PN declares that he has no competing interests.

Specialist Registrar

Liver Unit

Addenbrooke's Hospital

Cambridge

UK

Disclosures

Not disclosed.

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