Atopic dermatitis
Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- pruritus
- xerosis (dry skin)
- sites of skin involvement
Outros fatores diagnósticos
- erythema
- scaling
- vesicles
- papules
- keratosis pilaris
- excoriations
- lichenification
- hypopigmentation
Fatores de risco
- filaggrin gene mutation
- age <5 years
- family history of atopic dermatitis
- allergic rhinitis
- asthma
- active and passive exposure to smoke
- female sex
- African-American ethnicity
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- clinical diagnosis
Tests to avoid
- IgG testing
- radioallergosorbent test
Investigações a serem consideradas
- IgE levels
- skin-prick testing
- oral food challenge
- trial elimination diet
- patch testing
- skin biopsy
Algoritmo de tratamento
acute flare
chronic or relapsing disease
Colaboradores
Autores
Adelaide A. Hebert, MD
Professor & Director of Pediatric Dermatology
Clinical Specialist
Department of Dermatology and Pediatrics
University of Texas Health Sciences Center at Houston
Houston
TX
Declarações
AAH has received research grants paid to UTHealth McGovern Medical School Houston from Pfizer, GSK, Dermavant, Arcutis, and Novan; has received honoraria from Pfizer, Verrica, and Novan; and is on the data safety monitoring boards for GSK, Ortho Dermatologics, and Regeneron-Sanofi.
Alexander Jafari, MD
Dermatology Clinical Research Fellow
Department of Dermatology
University of Texas Health Science Center at Houston
Houston
TX
Declarações
AJ declares that he has no competing interests.
Matthew Dallo, MD
Clinical Research Fellow
Department of Dermatology
University of Texas Health Science Center at Houston
Houston
TX
Divulgaciones
MD declares that he has no competing interests.
Agradecimientos
Dr Adelaide A. Hebert, Dr Alexander Jafari, and Dr Matthew Dallo would like to gratefully acknowledge Dr Eugenio G. Galindo, Dr Quoc-Bao D. Nguyen, Dr Mary D. DarConte, Dr Christina M. Gelbard, and Dr Daniel A. Grabella, previous contributors to this topic.
Divulgaciones
EGG, QBDN, MDD, CMG, and DAG declare that they have no competing interests.
Revisores por pares
Amor Khachemoune, MD
Assistant Professor
New York University School of Medicine
NY
Divulgaciones
AK declares that he has no competing interests.
John English, MBBS, FRCP
Consultant Dermatologist
Department of Dermatology
Queen's Medical Centre
Nottingham University Hospitals
Nottingham
UK
Divulgaciones
JE declares that he has no competing interests.
Agradecimiento de los revisores por pares
Los temas de BMJ Best Practice se actualizan de forma continua de acuerdo con los desarrollos en la evidencia y en las guías. Los revisores por pares listados aquí han revisado el contenido al menos una vez durante la historia del tema.
Divulgaciones
Las afiliaciones y divulgaciones de los revisores por pares se refieren al momento de la revisión.
Referencias
Artículos principales
National Institute for Health and Care Excellence. Atopic eczema in under 12s: diagnosis and management. Sep 2025 [internet publication].Texto completo
European Dermatology Forum. Living EuroGuiDerm guideline for the systemic treatment of atopic eczema. Oct 2023 [internet publication].Texto completo
Davis DMR, Drucker AM, Alikhan A, et al. Guidelines of care for the management of atopic dermatitis in adults with phototherapy and systemic therapies. J Am Acad Dermatol. 2024 Feb;90(2):e43-56.Texto completo Resumen
Sidbury R, Alikhan A, Bercovitch L, et al. Guidelines of care for the management of atopic dermatitis in adults with topical therapies. J Am Acad Dermatol. 2023 Jan 11:S0190-9622(23)00004-X.Texto completo Resumen
Artículos de referencia
Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
Diferenciales
- Seborrheic dermatitis
- Irritant contact dermatitis
- Allergic contact dermatitis
Más DiferencialesGuías de práctica clínica
- Atopic eczema in under 12s: diagnosis and management
- Atopic eczema in under 12s: diagnosis and management
Más Guías de práctica clínicaFolletos para el paciente
Eczema
Más Folletos para el paciente
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