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Wrinkles

最后审阅: 19 Aug 2025
最后更新: 11 Jan 2022

小结

定义

病史和体格检查

关键诊断因素

  • presence of risk factors
  • age >40 years
  • chronic sun exposure
  • smoking
  • lines on face
  • horizontal neck folds
  • lines on dorsum of hands and wrists
  • dynamic lines
  • gravitational lines
  • deep wrinkles
  • fine wrinkles
完整详情

其他诊断因素

  • skin laxity
  • dyschromia
  • dermal elastosis
  • erythema
  • telangiectasia
  • textural changes
  • actinic keratoses
完整详情

危险因素

  • genetic susceptibility
  • age >40 years
  • white skin
  • hyperdynamic muscular activity
  • chronic sun exposure
  • smoking
  • pollution
  • low socioeconomic class
  • low BMI
完整详情

诊断性检查

首要检查

  • macrophotography
完整详情

需考虑的检查

  • skin biopsy
完整详情

新兴检查

  • profilometer
  • in vivo confocal microscopy

治疗流程

持续性治疗

no obvious wrinkles at rest or on animation

superficial wrinkles on animation only

deep wrinkles on animation only

superficial wrinkles at rest, deep wrinkles on animation

deep wrinkles and sagging skin at rest and deeper wrinkles on animation

撰稿人

作者

Dimitrios Dionyssiou, MD, PhD
Dimitrios Dionyssiou

Associate Professor in Plastic Surgery

Department of Plastic Surgery

Aristotle University of Thessaloniki

Thessaloniki

Greece

利益声明

DD declares that he has no competing interests.

Efterpi Demiri, MD, PhD
Efterpi Demiri

Professor in Plastic Surgery

Department of Plastic Surgery

Aristotle University of Thessaloniki

Thessaloniki

Greece

利益声明

ED declares that she has no competing interests.

Elisavet Lazaridou, MD, PhD
Elisavet Lazaridou

Professor

Second Department of Dermatology

Aristotle University of Thessaloniki

Thessaloniki

Greece

利益声明

EL declares that she has no competing interests.

同行评议者

George Hruza, MD

Clinical Professor of Dermatology and Otolaryngology

St. Louis University

St. Louis

Director

Laser and Dermatologic Surgery Center

Chesterfield

MO

利益声明

GH has been reimbursed by Allergan, Dermik, and Colbar Life Sciences to attend educational symposia and has also been paid to teach other physicians. GH is a consultant for Ulthera and has received equipment for research from Syneron. GH is an author of a reference cited in this topic.

Stephanos Papanastasiou, FRCSEd, MSc, EBOPRAS, FESSH

Consultant Plastic Surgeon

Lister Hospital

Stevenage

UK

利益声明

SP declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol. 1988 Jun;124(6):869-71. 摘要

Bhawan J, Andersen W, Lee J, et al. Photoaging versus intrinsic aging: a morphologic assessment of facial skin. J Cutan Pathol. 1995 Apr;22(2):154-9. 摘要

Callaghan TM, Wilhelm KP. A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part 2: clinical perspectives and clinical methods in the evaluation of ageing skin. Int J Cosmet Sci. 2008 Oct;30(5):323-32. 摘要

Ogden S, Griffiths TW. A review of minimally invasive cosmetic procedures. Br J Dermatol. 2008 Nov;159(5):1036-50. 摘要

Klein AW. Techniques for soft tissue augmentation: an 'A to Z'. Am J Clin Dermatol. 2006;7(2):107-20. 摘要

Papadavid E, Katsambas A. Lasers for facial rejuvenation: a review. Int J Dermatol. 2003 Jun;42(6):480-7. 摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Wrinkles images
  • 鉴别诊断

    • Cutis laxa
    • Werner syndrome (progeria or pangeria)
    • Xeroderma pigmentosum
    更多 鉴别诊断
  • 指南

    • Guidelines for topical photodynamic therapy: update
    • Global consensus guidelines for the injection of diluted and hyperdiluted calcium hydroxylapatite for skin tightening
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  • 患者教育信息

    Wrinkles

    更多 患者教育信息
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