Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- age >40 years
- chronic sun exposure
- smoking
- lines on face
- horizontal neck folds
- lines on dorsum of hands and wrists
- dynamic lines
- gravitational lines
- deep wrinkles
- fine wrinkles
Other diagnostic factors
- skin laxity
- dyschromia
- dermal elastosis
- erythema
- telangiectasia
- textural changes
- actinic keratoses
Risk factors
- genetic susceptibility
- age >40 years
- white skin
- hyperdynamic muscular activity
- chronic sun exposure
- smoking
- pollution
- low socioeconomic class
- low BMI
Diagnostic tests
1st tests to order
- macrophotography
Tests to consider
- skin biopsy
Emerging tests
- profilometer
- in vivo confocal microscopy
Treatment algorithm
no obvious wrinkles at rest or on animation
superficial wrinkles on animation only
deep wrinkles on animation only
superficial wrinkles at rest, deep wrinkles on animation
deep wrinkles and sagging skin at rest and deeper wrinkles on animation
Contributors
Authors
Dimitrios Dionyssiou, MD, PhD
Associate Professor in Plastic Surgery
Department of Plastic Surgery
Aristotle University of Thessaloniki
Thessaloniki
Greece
Disclosures
DD declares that he has no competing interests.
Efterpi Demiri, MD, PhD
Professor in Plastic Surgery
Department of Plastic Surgery
Aristotle University of Thessaloniki
Thessaloniki
Greece
Disclosures
ED declares that she has no competing interests.
Elisavet Lazaridou, MD, PhD
Professor
Second Department of Dermatology
Aristotle University of Thessaloniki
Thessaloniki
Greece
Disclosures
EL declares that she has no competing interests.
Peer reviewers
George Hruza, MD
Clinical Professor of Dermatology and Otolaryngology
St. Louis University
St. Louis
Director
Laser and Dermatologic Surgery Center
Chesterfield
MO
Disclosures
GH has been reimbursed by Allergan, Dermik, and Colbar Life Sciences to attend educational symposia and has also been paid to teach other physicians. GH is a consultant for Ulthera and has received equipment for research from Syneron. GH is an author of a reference cited in this topic.
Stephanos Papanastasiou, FRCSEd, MSc, EBOPRAS, FESSH
Consultant Plastic Surgeon
Lister Hospital
Stevenage
UK
Disclosures
SP declares that he has no competing interests.
Differentials
- Cutis laxa
- Werner syndrome (progeria or pangeria)
- Xeroderma pigmentosum
More DifferentialsGuidelines
- Guidelines for topical photodynamic therapy: update
- Global consensus guidelines for the injection of diluted and hyperdiluted calcium hydroxylapatite for skin tightening
More GuidelinesPatient information
Wrinkles
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