Evaluation of eosinophilia

Last reviewed: 12 Nov 2024
Last updated: 23 Jul 2024

Summary

Differentials

Common

  • Ascariasis
  • Strongyloidiasis
  • Schistosomiasis
  • Trichinellosis
  • Pemphigus
  • Bullous pemphigoid
  • Asthma
  • Eczema
  • Allergic rhinitis
Full details

Uncommon

  • Clonorchiasis
  • Fascioliasis
  • Fasciolopsiasis
  • Opisthorchiasis
  • Filariasis
  • Gnathostomiasis
  • Toxocariasis
  • Paragonimiasis
  • Ancylostoma caninum infestation
  • Coccidioidomycosis
  • Pemphigoid gestationis
  • Drug hypersensitivity
  • Drug rash with eosinophilia and systemic symptoms (DRESS)
  • Allergic bronchopulmonary aspergillosis
  • Eosinophilic granulomatosis with polyangiitis
  • Eosinophilic esophagitis
  • Eosinophilic gastroenteritis
  • Eosinophilic cellulitis (Wells syndrome)
  • Chronic eosinophilic leukemia
  • Other leukemias
  • Non-Hodgkin lymphoma
  • Hodgkin lymphoma
  • Nonhematologic malignancy-associated hypereosinophilia
  • Lymphocytic variant of hypereosinophilic syndrome
  • Idiopathic hypereosinophilic syndrome
  • Wiskott-Aldrich syndrome
  • Job syndrome
  • Hyperimmunoglobulin E syndrome
  • Severe combined immune deficiency due to adenosine deaminase deficiency
  • Omenn syndrome
  • immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome
  • Autoimmune lymphoproliferative syndrome (ALPS)
  • Loeys-Dietz syndrome
  • Comel-Netherton syndrome
  • Severe dermatitis, multiple allergies, and metabolic wasting (SAM) syndrome
  • Muscular sarcocystosis
  • Cystoisospora belli (formerly Isospora belli) infection
  • Anisakiasis
  • Loiasis
Full details

Contributors

Authors

Barbara J. Bain, MBBS, FRACP, FRCPath

Professor of Diagnostic Haematology

St Mary's Hospital Campus

Imperial College London

London

UK

Disclosures

BJB is an author of a number of references cited in this topic.

James Uprichard, MBBS, BSc, PhD, FRCP, FRCPath

Consultant Haematologist

Department of Haematology

St George's University Hospitals NHS Foundation Trust

London

UK

Disclosures

JU declares that he has no competing interests.

Peer reviewers

Zeinab Afify, MD

Professor of Pediatrics

Department of Pediatrics

Division of Pediatric Hematology Oncology

University of Utah

UT

Disclosures

ZA declares that she has no competing interests.

Jan Cools, PhD

Associate Professor

Department of Molecular and Developmental Genetics

Katholieke Universiteit Leuven

Leuven

Belgium

Disclosures

JC is an author of a reference cited in this topic.

Use of this content is subject to our disclaimer