Summary
Definition
History and exam
Key diagnostic factors
- geographic exposure
- skin exposure to contaminated freshwater
- abdominal pain
- hematuria
- hematemesis
Other diagnostic factors
- school age (4 to 15 years)
- occupational exposure
- rash
- fever
- dysuria
- hepatosplenomegaly
- dyspnea
- bloody diarrhea
- pelvic pain
- infertility or history of ectopic pregnancy
- ascites
- genital ulcers
Risk factors
- skin exposure to contaminated freshwater
- travel to endemic areas
- age 4 to 15 years
Diagnostic investigations
1st investigations to order
- stool or urine microscopy
- urinalysis
- CBC
- blood culture
- thick and thin blood smears
Investigations to consider
- serology
- LFTs
- renal function tests
- abdominal ultrasound
- tissue biopsy
- CT or MRI abdomen
- MRI brain and spinal cord
- CXR
- CT chest
- urinary circulating anodic antigen (CAA)
- schistosome DNA/RNA
Treatment algorithm
Contributors
Authors VIEW ALL
Professor of Medicine
Division of Infectious Diseases
University of Alabama at Birmingham
Birmingham
AL
Disclosures
JMR declares that he has no competing interests.
Assistant Professor
Division of Infectious Diseases
Department of Medicine
Medical College of Wisconsin
Milwaukee
WI
Disclosures
NG declares that he has no competing interests.
Dr J. Martin Rodriguez and Dr Nathan Gundacker would like to gratefully acknowledge the late Dr Ildefonso Tellez, who was previously a co-contributor to this topic. Dr Rodriguez would also like to gratefully acknowledge Dr Arlene Dent and Dr Charles H. King, previous contributors to this topic. IT declared that he had no competing interests. AD and CHK also declare that they have no competing interests.
Peer reviewers VIEW ALL
Professor
Medical College of Wisconsin
Milwaukee
WI
Disclosures
RO declares that he has no competing interests.
Professor
Faculty of Medicine
Federal University of Minas Gerais
Belo Horizonte
Minas Gerais
Brazil
Disclosures
JRL declares that he has no competing interests.
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