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Urinary tract infections in children

最后审阅: 10 Oct 2025
最后更新: 05 Jun 2025

小结

定义

病史和体格检查

关键诊断因素

  • fever >102.2°F (>39°C)
  • irritability (neonates and infants)
  • poor feeding (neonates and infants)
  • suprapubic tenderness
  • costovertebral angle tenderness
完整详情

其他诊断因素

  • foul-smelling urine (infants, older children, and adolescents)
  • dysuria (preschool age, older children, and adolescents)
  • urinary frequency (older children and adolescents)
  • abdominal/flank pain (infants, older children, and adolescents)
  • vomiting
  • ill appearance (neonates)
  • gross hematuria (older children and adolescents)
  • new-onset urinary incontinence (toddlers, older children, and adolescents)
完整详情

危险因素

  • age <1 year
  • female sex
  • uncircumcised boys in the first year of life
  • previous UTI
  • bladder and bowel dysfunction
  • vesicoureteral reflux
  • sexual activity
  • no history of breastfeeding
  • anatomic abnormalities or previous surgery to the urinary tract
  • immunosuppression
  • protein-energy malnutrition
完整详情

诊断性检查

首要检查

  • urine dipstick
  • urine microscopy
  • urine culture
完整详情

需考虑的检查

  • urine flow cytometry
  • blood culture
  • complete blood count
  • inflammatory markers
  • fungus urine culture
  • serum creatinine, BUN and electrolytes
  • renal and/or bladder ultrasound
  • dimercaptosuccinic acid (DMSA) scan
  • voiding cystourethrogram (VCUG)
完整详情

治疗流程

初步治疗

vesicoureteral reflux: no history of febrile UTIs

急症处理

age ≤2 months

age >2 months

持续性治疗

recurrent UTIs

撰稿人

作者

Joana Dos Santos, MD, MHSc, FRCPC

Assistant Professor of Pediatrics

Medical Pediatric Urologist

The Hospital for Sick Children

Toronto

Ontario

Canada

利益声明

JDS declares that she has no competing interests.

鸣谢

Dr Joana Dos Santos would like to gratefully acknowledge Dr Beatrice Goilav, Dr Frederick Kaskel, Dr Mary Anne Jackson, and Dr Rene VanDeVoorde, previous contributors to this topic.

利益声明

BG, FK, MAJ, and RV declare that they have no competing interests.

同行评议者

Martin Koyle, MD, MSc, FAAP, FACS, FRCS(Eng), FRCSC

Professor

Department of Surgery and Institute of Health Policy, Management and Evaluation

Staff Pediatric Urologist

The Hospital for Sick Children

Toronto

Ontario

Canada

利益声明

MK declares that he has no competing interests.

Daniel T. Keefe, MD, FRCSC

Pediatric Urology Fellow

The Hospital for Sick Children

Toronto

Ontario

Canada

利益声明

DTK declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

European Association of Urology. Guidelines on paediatric urology. 2024 [internet publication].全文

National Institute for Health and Care Excellence. Urinary tract infection in under 16s: diagnosis and management. Jul 2022 [internet publication].全文

Mattoo TK, Shaikh N, Nelson CP. Contemporary management of urinary tract infection in children. Pediatrics. 2021 Feb;147(2):e2020012138.全文  摘要

American College of Radiology. ACR appropriateness criteria: urinary tract infection - child. 2023 [internet publication].全文

Peters CA, Skoog SJ, Arant BS Jr, et al; American Urological Association. Management and screening of primary vesicoureteral reflux in children: AUA guideline. 2017 [internet publication].全文

参考文献

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