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Asthma in children

Última revisão das evidências: 21 Mar 2026
Última atualização do tópico: 24 Feb 2026

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • wheezing episode triggers
  • increased work of breathing
  • features of atopic disease
  • history of response to treatment within appropriate time frame
  • family history of asthma
  • history of passive or active tobacco smoking
Detalhes completos

Outros fatores diagnósticos

  • age >3 years
  • dry nighttime cough
  • dyspnea on exertion
  • expiratory wheezing
  • chest wall deformity
Detalhes completos

Fatores de risco

  • allergic sensitization
  • atopic disease
  • respiratory tract infections in early life
  • biomarkers of type 2 inflammation (serum eosinophils and fractional exhaled nitric oxide)
  • family history of asthma or atopy
  • gene polymorphisms and epigenetics
  • passive or active cigarette smoking
  • vaping
  • maternal smoking in pregnancy
  • abnormal lung function and airway hyperresponsiveness
  • indoor and outdoor air pollution
  • extreme weather events
  • low socioeconomic status
  • pesticide exposure
  • male sex
  • obesity
  • gastroesophageal reflux disease (GERD)
  • obstructive sleep apnea (OSA)
  • assisted reproductive technologies
  • cesarean section
  • intestinal microbiota
  • acid-suppressive drug use in pregnancy and childhood
  • acetaminophen use in pregnancy
  • antibiotic use in pregnancy
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • spirometry
  • peak expiratory flow (PEF)
  • response to bronchodilator
Detalhes completos

Investigações a serem consideradas

  • fractional expired nitric oxide (FeNO)
  • blood eosinophil count
  • airway challenge tests
  • exercise challenge test
  • sweat test
  • sputum culture
  • skin prick testing
  • chest x-ray
  • electron micrograph ciliary studies
  • chest CT
  • sinus CT
  • bronchoscopy
Detalhes completos

Novos exames

  • sputum eosinophilia

Algoritmo de tratamento

CONTÍNUA

age 0 to 5 years

age 6 to 11 years

Colaboradores

Autores

Paul D. Robinson, MBChB, MRCPCH, FRACP, PhD, ATSF

Respiratory and Sleep Physician

Queensland Children's Hospital

Conjoint Professor

Child Health Research Centre

University of Queensland

Brisbane

Queensland

Australia

Divulgaciones

PDR declares that he has no competing interests.

Anne Chang, MBBS, FRACP, MPHTM, PhD, FAPSR, FThorSoc, FAHMS

Professor

Respiratory and Sleep Physician

Queensland Children's Hospital

Queensland University of Technology

Brisbane

Menzies School of Health Research

Charles Darwin University

Darwin

Australia

Divulgaciones

AC is an author of a number of references cited in this topic.

Revisores por pares

Kenan Haver, MD

Associate Professor of Pediatrics, Harvard Medical School

Boston Children's Hospital

Division of Pulmonary Medicine

Boston

MA

Divulgaciones

KH receives royalties from UpToDate.

Peter Griffiths, MBChB

General Practitioner

Harborne Medical Practice

Birmingham

UK

Divulgaciones

PG declares that he has no competing interests.

Agradecimiento de los revisores por pares

Los temas de BMJ Best Practice se actualizan de forma continua de acuerdo con los desarrollos en la evidencia y en las guías. Los revisores por pares listados aquí han revisado el contenido al menos una vez durante la historia del tema.

Divulgaciones

Las afiliaciones y divulgaciones de los revisores por pares se refieren al momento de la revisión.

Referencias

Nuestros equipos internos de evidencia y editoriales colaboran con colaboradores expertos internacionales y revisores pares para garantizar que brindemos acceso a la información más clínicamente relevante posible.

Artículos principales

Global Initiative for Asthma. 2025 global strategy for asthma management and prevention. Nov 2025 [internet publication].Texto completo

National Institute for Health and Care Excellence. Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN). Nov 2024 [internet publication].Texto completo

National Institute for Health and Care Excellence. Asthma pathway (BTS, NICE, SIGN). Nov 2024 [internet publication].Texto completo

Expert Panel Working Group of the National Heart, Lung, and Blood Institute (NHLBI) administered and coordinated National Asthma Education and Prevention Program Coordinating Committee (NAEPPCC), Cloutier MM, Baptist AP, et al. 2020 focused updates to the asthma management guidelines: a report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group. J Allergy Clin Immunol. 2020 Dec;146(6):1217-70.Texto completo  Resumen

National Heart, Lung, and Blood Institute; National Asthma Education and Prevention Program. Guidelines for the diagnosis and management of asthma. Aug 2007 [internet publication].Texto completo

Artículos de referencia

Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
  • Diferenciales

    • Bronchiolitis
    • Episodic (viral) wheeze
    • Inhaled foreign body
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  • Guías de práctica clínica

    • Global strategy for asthma management and prevention
    • Asthma pathway (BTS, NICE, SIGN)
    Más Guías de práctica clínica
  • Folletos para el paciente

    Asthma in children: what is it?

    Asthma in children: types of inhalers

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  • Videos

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    Polyphonic wheeze

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