Evaluation of lower extremity mononeuropathy

Last reviewed: 10 Nov 2024
Last updated: 10 Jan 2024

Summary

Differentials

Common

  • Diabetic amyotrophy
  • Lumbosacral radiculopathy
  • Meralgia paresthetica
  • Peroneal neuropathy
  • Morton neuroma
Full details

Uncommon

  • Lumbosacral plexopathy (non-neoplastic compressive)
  • Obturator neuropathy
  • Sciatic neuropathy
  • Tarsal tunnel syndrome
  • Tibial neuropathy
  • Femoral mononeuropathy
  • Hereditary neuropathy with liability to pressure palsies (HNPP)
  • HIV
  • Herpes zoster
  • Herpes simplex
  • Epstein-Barr virus
  • Cytomegalovirus
  • Lyme disease
  • Leprosy
  • Peripheral nerve vasculitis
  • Sarcoidosis
  • Sjogren syndrome
  • Rheumatoid arthritis
  • Acquired demyelinating sensorimotor polyneuropathy
  • Lumbosacral plexopathy (inflammatory)
  • Lumbosacral plexopathy (neoplastic compressive)
  • Radiation-induced plexopathy
  • Lymphoma
  • Amyloidosis
  • Paraneoplastic immune-mediated attacks
  • Nerve sheath tumors
Full details

Contributors

Authors

Kevin R. Scott, MD

Clinical Neurologist

Colorado Springs Neurological Associates

Colorado Springs

CO

Disclosures

KRS declares that he has no competing interests.

Acknowledgements

Dr Kevin R Scott would like to gratefully acknowledge Dr Milind J. Kothari, a previous contributor to this topic.

Disclosures

MJK declares that he has no competing interests.

Peer reviewers

Nizar Souayah, MD

Assistant Professor of Neurology

Director of EMG Laboratory & Peripheral Neuropathy Center

Department of Neurology & Neurosciences

New Jersey Medical School

Newark

NJ

Disclosures

NS declares that he has no competing interests.

Giuseppe Lauria, MD

Senior Consultant

Neuromuscular Diseases Unit

IRCCS Foundation "Carlo Besta" Neurological Institute

Milan

Italy

Disclosures

GL declares that he has no competing interests.

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