Last reviewed: 24 Sep 2021
Last updated: 13 Feb 2018

Summary

Definition

History and exam

Key diagnostic factors

  • vomiting
  • explosive passage of liquid and foul stools
  • abdominal distension
  • delayed passage of meconium
  • fever
  • failure to thrive

Risk factors

  • Down syndrome
  • multiple endocrine neoplasia type IIA
  • male gender
  • gene mutations (chromosome 10 and 21)

Diagnostic investigations

Treatment algorithm

Contributors

Authors

Andrea Bischoff, MD

Pediatric Surgeon

Assistant Director of the International Center for Colorectal and Urogenital Care

Children's Hospital Colorado

Associate Professor of Surgery

University of Colorado

Aurora

CO

Disclosures

AB is a co-author of several references cited in this monograph.

Alberto Peña, MD

Pediatric Surgeon

Director of the International Center for Colorectal and Urogenital Care

Children's Hospital Colorado

Professor of Surgery

University of Colorado

Aurora

CO

Disclosures

AP is a co-author of several references cited in this monograph.

Acknowledgements

Dr Andrea Bischoff and Dr Alberto Peña would like to gratefully acknowledge Dr Marc A. Levitt, a previous contributor to this monograph. MAL declares that he has no competing interests.

Peer reviewers

Ivo de Blaauw, MD, PHD

Pediatric Surgeon

Radboud University Nijmegen

Academic Medical Center

Nijmegen

Netherlands

Disclosures

IdB declares that he has no competing interests.

Jose Manuel Tovilla, MD

Colorectal Pediatric Surgeon

Chief of the Colorectal Clinic

Hospital Infantil de Mexico Federico Gomez

Mexico

Disclosures

JMT declares that he has no competing interests.

Daniel P. Doody, MD

Pediatric Surgeon

Department of Pediatric Surgery

Massachusetts General Hospital

Boston

MA

Disclosures

DPD declares that he has no competing interests.

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