小结
定义
病史和体格检查
关键诊断因素
- headache
- neurologic deficit
- seizure
- history of radiation exposure
其他诊断因素
- family history of brain tumor or neurofibromatosis 2 (NF2)
- history of breast cancer
- history of exogenous hormone exposure
- cognitive deficit
- vertigo/dizziness
危险因素
- ionizing radiation
- genetic predisposition
- hormones: endogenous and exogenous
- head trauma
诊断性检查
首要检查
- MRI brain or spine with and without contrast
需考虑的检查
- CT brain or spine
- somatostatin receptor PET/CT
- cerebral angiography
- histopathology of surgical resection
治疗流程
good surgical candidate
poor surgical candidate
recurrent or progressive tumor following initial treatment
撰稿人
作者
Stephen T. Magill, MD, PhD
Assistant Professor
Lou and Jean Malnati Brain Tumor Institute
Robert Lurie Comprehensive Cancer Center
Department of Neurological Surgery
Northwestern University Feinberg School of Medicine
Chicago
IL
Divulgaciones
STM has authored several articles cited in this topic.
Agradecimientos
Dr Stephen T. Magill would like to gratefully acknowledge Professor William T. Couldwell and Dr Jayson A. Neil, previous contributors to this topic.
Divulgaciones
WTC is an author of several references cited in this topic. JAN declares that he has no competing interests.
Revisores por pares
Marc Chamberlain, MD
Professor of Neurology
Moffitt Cancer Center and Research Institute
University of Washington
Seattle
WA
Divulgaciones
MC is an author of several references cited in this topic.
Ian McCutcheon, MD
Professor of Neurosurgery
The University of Texas M. D. Anderson Cancer Center
Houston
TX
Divulgaciones
IM declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Referencias
Artículos principales
World Health Organization Classification of Tumours Editorial Board. WHO classification of tumours of the central nervous system. 5th Edition. France: IARC; 2021.
Louis DN, Perry A, Wesseling P, et al. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol. 2021 Aug 2;23(8):1231-51.Texto completo Resumen
National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: central nervous system cancers [internet publication].Texto completo
Goldbrunner R, Stavrinou P, Jenkinson MD, et al. EANO guideline on the diagnosis and management of meningiomas. Neuro Oncol. 2021 Nov 2;23(11):1821-34.Texto completo Resumen
Artículos de referencia
Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
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Más DiferencialesGuías de práctica clínica
- NCCN guidelines: central nervous system cancers
- American College of Radiology (ACR) appropriateness criteria: brain tumors
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