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Breast cancer in situ

ბოლო მიმოხილვა: 12 Dec 2025
ბოლო განახლება: 30 Apr 2025

შეჯამება

განსაზღვრება

ანამნეზი და გასინჯვა

ძირითადი დიაგნოსტიკური ფაქტორები

  • family history of breast cancer
სრული ტექსტი

სხვა დიაგნოსტიკური ფაქტორები

  • nipple discharge
  • breast lump
  • eczema-like rash on nipple
  • ulceration
სრული ტექსტი

რისკფაქტორები

  • family history of breast cancer
  • benign breast disease on prior biopsy
  • hereditary breast ovarian cancer syndrome
  • Li-Fraumeni syndrome
  • Cowden syndrome
  • hereditary diffuse gastric cancer (HDGC)
  • Peutz-Jeghers syndrome
  • Klinefelter syndrome
  • older age at menopause
  • older age at first full-term pregnancy
  • nulliparity
  • low physical activity
  • high vitamin A intake
  • ataxia telangiectasia
სრული ტექსტი

დიაგნოსტიკური კვლევები

1-ად შესაკვეთი გამოკვლევები

  • mammography
სრული ტექსტი

Tests to avoid

  • PET, CT, or radionuclide bone scans
სრული ტექსტი

გასათვალისწინებელი კვლევები

  • core needle biopsy
  • excisional biopsy
  • sentinel lymph node biopsy (SLNB)
  • breast magnetic resonance imaging (MRI)
  • breast ultrasound
  • hormone receptor testing
  • genetic evaluation
სრული ტექსტი

მკურნალობის ალგორითმი

მწვავე

women with low-risk ductal carcinoma in situ

women with high-risk DCIS; all men with DCIS

lobular carcinoma in situ

მიმდინარე

local recurrence of DCIS

კონტრიბუტორები

ავტორები

Edward R. Sauter, MD, PhD
Edward R. Sauter

Medical Officer

Breast and Gynecologic Cancer Working Group

Division of Cancer Prevention

National Cancer Institute

Bethesda

MD

გაფრთხილება:

ERS is an author of a reference cited in this topic.

მადლიერება

Dr Edward R. Sauter would like to gratefully acknowledge Dr Rachel L. Ruhlen, a previous contributor to this topic.

გაფრთხილება:

RLR declares that she has no competing interests.

რეცენზენტები

Carla Boetes, MD, PhD

Radiologist

Radboud University Nijmegen Medical Centre

Nijmegen

The Netherlands

გაფრთხილება:

CB is an author of a number of references cited in this topic.

Alessandra Balduzzi, MD

Assistant in the Division of Medical Oncology

European Institute of Oncology

Milan

Italy

გაფრთხილება:

AB declares that she has no competing interests.

Kala Visvanathan, MBBS, FRACP, MHS

Associate Professor in Epidemiology and Medical Oncology

Johns Hopkins School of Medicine and Bloomberg School of Public Health

Baltimore

MD

Disclosures

KV is an author of a number of references cited in this topic.

Glyn T. Neades, MB ChB, FRCS(Glas), FRCS(Ed), ChM

Consultant Surgeon and Honorary Senior Lecturer

Edinburgh Breast Unit

Western General Hospital

Edinburgh

UK

Divulgaciones

GTN is a principal investigator for the IBIS-II trial, and is an author of a guideline cited in this topic.

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Divulgaciones

Las afiliaciones y divulgaciones de los revisores por pares se refieren al momento de la revisión.

Referencias

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Artículos principales

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: breast cancer risk reduction [internet publication].Texto completo

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: breast cancer [internet publication].Texto completo

Loibl S, André F, Bachelot T, et al. Early breast cancer: ESMO clinical practice guideline for diagnosis, treatment and follow-up. Ann Oncol. 2024 Feb;35(2):159-82.Texto completo

Morrow M, Van Zee KJ, Solin LJ, et al. Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in ductal carcinoma in situ. J Clin Oncol. 2016 Nov 20;34(33):4040-6. [Reaffirmed 2019.]Texto completo  Resumen

Artículos de referencia

Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
  • Breast cancer in situ images
  • Diferenciales

    • Invasive breast cancer
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  • Guías de práctica clínica

    • NCCN clinical practice guidelines in oncology: breast cancer screening and diagnosis
    • NCCN clinical practice guidelines in oncology: breast cancer risk reduction​
    Más Guías de práctica clínica
  • Patient information

    Breast cancer: DCIS (very early breast cancer) in women

    Breast cancer, locally advanced: what is it?

    More Patient information
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