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Pyloric stenosis

最后审阅: 19 Aug 2025
最后更新: 05 Jan 2024

小结

定义

病史和体格检查

关键诊断因素

  • first-born male infant
  • non-bilious projectile vomiting
  • 2 to 12 weeks old
  • upper abdominal mass
  • peristaltic waves
完整详情

其他诊断因素

  • family history of pyloric stenosis
  • multiple formula changes
  • tachycardia
  • decreased wet nappies
  • dry mucous membranes
  • flat or depressed fontanelles
  • constipation
  • poor weight gain
  • irritability
完整详情

危险因素

  • prematurity
  • early exposure to erythromycin
  • exposure to prostaglandins
  • maternal exposure to macrolides
  • geographic location/ethnic background
  • first-born male infant
  • family history of pyloric stenosis
完整详情

诊断性检查

首要检查

  • chemistry panel
  • ultrasound abdomen
完整详情

治疗流程

急症处理

all patients

撰稿人

作者

Catherine J. Hunter, MD

Professor of Surgery and Division Chief of Pediatric Surgery

Oklahoma Children’s Hospital

The University of Oklahoma College of Medicine

Oklahoma City

OK

利益声明

CJH declares that she has no competing interests.

鸣谢

Dr Catherine Hunter would like to gratefully acknowledge Dr Samuel C. Klonoski, Dr Jeffrey S. Upperman, Dr Yigit S. Guner, and Dr Arturo Aranda, previous contributors to this topic. SCK, JSU, YSG, and AA declare that they have no competing interests.

同行评议者

Evan Nadler, MD

Assistant Professor of Surgery

Department of Surgery

Division of Pediatric Surgery

NYU Medical Center

New York

NY

利益声明

EN declares that he has no competing interests.

Lewis Spitz, PhD FRCS MD (Hon), FRCPCH FAAP (Hon), FCS (SA) (Hon)

Emeritus Nuffield Professor of Paediatric Surgery

Institute of Child Health

University College

London

UK

利益声明

LS declares that he has no competing interests.

Ruth Hallows, BSc, MB BS, FRCS, FRCS III (Paediatric Surgery)

Consultant in Paediatric and Neonatal Surgery

Royal Alexandra Children's Hospital

Brighton

UK

利益声明

RH declares that she has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Aspelund G, Langer JC. Current management of hypertrophic pyloric stenosis. Semin Pediatr Surg. 2007 Feb;16(1):27-33. 摘要

Expert Panel on Pediatric Imaging., Alazraki AL, Rigsby CK, et al. ACR Appropriateness Criteria® Vomiting in infants. J Am Coll Radiol. 2020 Nov;17(11s):S505-S515.全文  摘要

Staerkle RF, Lunger F, Fink L, et al. Open versus laparoscopic pyloromyotomy for pyloric stenosis. Cochrane Database Syst Rev. 2021 Mar 9;3:CD012827.全文  摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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