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Migraine headache in children

Last reviewed: 19 Mar 2025
Last updated: 17 Apr 2025

Summary

Definition

History and exam

Key diagnostic factors

  • severe episodic headache
  • nausea and vomiting
  • light and noise sensitivity
  • functional impact
  • aura symptoms
  • throbbing character
Full details

Risk factors

  • family history of migraine
  • female sex and hormonal changes
  • poor sleep quality
  • stress
  • medication overuse
  • periodic syndromes
Full details

Diagnostic investigations

1st investigations to order

  • clinical diagnosis
Full details

Investigations to consider

  • brain MRI
  • electroencephalogram
  • lumbar puncture
  • erythrocyte sedimentation rate (ESR) and CRP
  • head CT
Full details

Treatment algorithm

ACUTE

acute episode

ONGOING

≥1 significant migraine per week

Contributors

Authors

Cristian Ionita, MD

Associate Professor of Clinical Pediatrics (Neurology)

Yale School of Medicine

New Haven

CT

Disclosures

CI declares that he has no competing interests.

Acknowledgements

Dr Christian Ionita would like to gratefully acknowledge Dr Nick Barnes, a previous contributor to this topic.

Disclosures

NB declares that he has no competing interests.

Peer reviewers

Kenneth Mack, MD, PhD

Medical Director

Mayo Clinic Pediatric Center

Rochester

MN

Disclosures

KM declares that he has no competing interests.

Tony McShane, MBBS

Consultant Paediatric Neurologist

John Radcliffe Hospital

Oxford

UK

Disclosures

TM declares that he has no competing interests.

Sandeep Jayawant, MBBS

Consultant Paediatric Neurologist

John Radcliffe Hospital

Oxford

UK

Disclosures

SJ declares that he has no competing interests.

Howard S. Jacobs, MD

Associate Professor

Co-Director Pediatric Headache Clinic

University of Maryland School of Medicine

Baltimore

MD

Disclosures

HSJ declares that he has no competing interests.

  • Differentials

    • Tension-type headache
    • Medication-overuse headache
    • Post-traumatic headache
    More Differentials
  • Guidelines

    • Practice guideline update: acute treatment of migraine in children and adolescents
    • Practice guideline update: pharmacologic treatment for pediatric migraine prevention
    More Guidelines
  • Patient information

    Migraine in children

    Migraine in children: medicines to prevent attacks

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