Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- cold exposure and body temperature <35°C (<95°F)
- cognitive impairment
- shivering
- frostbite
Other diagnostic factors
- tachypnoea, tachycardia, hypertension
- respiratory depression, bradycardia, hypotension
- coma and apnoea
- cold-induced diuresis
Risk factors
- general anaesthetic use
- older age
- very young age
- immobility
- substance misuse
- impaired cognition
- hypothyroidism
- stroke
- Parkinson's disease
- homelessness
- gram-negative septicaemia
- neuroleptic medication
- beta-blocker medication
- sedative hypnotic medication
Diagnostic investigations
1st investigations to order
- core temperature measurement
- 12-lead ECG
- blood glucose
- blood gas
- serum urea, electrolytes, and creatinine
- FBC
- clotting screen
- chest x-ray
Investigations to consider
- serum creatine kinase
- myoglobin levels
- end-tidal CO₂
- ultrasound
Treatment algorithm
moderate or severe hypothermia in cardiac arrest: ≤32°C (≤90°F)
moderate or severe hypothermia not in cardiac arrest: ≤32°C (≤90°F)
mild hypothermia: >32°C to 35°C (>90°F to 95°F)
Contributors
Expert advisers
Alexander Alexiou, MBBS, BSc, DCH, FRCEM, Dip IMC RCSEd
Emergency Medicine Consultant
Barts Health NHS Trust
Physician Response Unit Consultant
London’s Air Ambulance
Royal London Hospital
London
UK
Disclosures
AA declares that he has no competing interests.
Melvyn Jenkins-Welch, MBBS, BSc, MSc, FRCA, FFICM
Consultant Critical Care Medicine
Cardiff and Vale ULHB
Cardiff
UK
Disclosures
MJW declares that he has no competing interests.
Acknowledgements
BMJ Best Practice would like to gratefully acknowledge the previous expert contributors, whose work has been retained in parts of the content:
Emmanuel Atta Agaba, MD, FRCSEd, FACS
Attending Surgeon
Assistant Professor of Surgery
Montefiore Medical Center at Albert Einstein College of Medicine
Bronx
NY
Rafael Barrera, MD, FACP
Director
Surgical Intensive Care Unit
Long Island Jewish Medical Center
New Hyde Park
NY
Disclosures
EAA and RB declare that they have no competing interests.
Peer reviewers
Patrick Morgan, MBChB, FRCA, FFICM, Dip IMC RCSEd, DiMM
Consultant in Anaesthesia
North Bristol NHS Trust
Bristol
Pre-hospital and Retrieval Doctor
Emergency Medical Retrieval and Transfer Service (EMRTS) Cymru
UK
Disclosures
PM is Medical Director, HM coastguard (UK). PM has been a medical expert witness in hypothermia, cold water-immersion and drowning. PM is a Research Associate/student at the Extreme Environments Laboratory, University of Portsmouth.
Editors
Annabel Sidwell
Section Editor, BMJ Best Practice
Disclosures
AS declares that she has no competing interests.
Tannaz Aliabadi-Oglesby
Lead Section Editor, BMJ Best Practice
Disclosures
TAO declares that she has no competing interests.
Adam Mitchell
Drug Editor, BMJ Best Practice
Disclosures
AM declares that he has no competing interests.
Julie Costello
Comorbidities Editor, BMJ Best Practice
Disclosures
JC declares that she has no competing interests.
Differentials
- Sepsis
- Hypothyroidism
More DifferentialsGuidelines
- European Resuscitation Council guidelines for resuscitation 2021
- Clinical practice guidelines for the out-of-hospital evaluation and treatment of accidental hypothermia
More GuidelinesCalculators
Glasgow Coma Scale
More Calculators- Log in or subscribe to access all of BMJ Best Practice
Use of this content is subject to our disclaimer