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Obstructive uropathy

最后审阅: 24 Sep 2025
最后更新: 13 Sep 2024

小结

定义

病史和体格检查

关键诊断因素

  • signs of early organ dysfunction (tachypnea, tachycardia, hypotension, altered mental state) in a patient with suspected sepsis
  • flank pain
  • fever
  • lower urinary tract symptoms
  • distended abdomen/palpable bladder
  • inability to urinate
  • enlarged or hard nodular prostate on rectal exam
  • costovertebral angle tenderness
  • neurologic disease (e.g., spinal cord injury, multiple sclerosis)
完整详情

其他诊断因素

  • hematuria
  • increasing age
  • meatal narrowing
  • pelvic or abdominal malignancy
  • previous urethral instrumentation
  • urinary tract infection in a child
  • pelvic mass on internal exam
  • weight loss and lymphadenopathy
  • recurrent urinary tract infections
  • urinary incontinence
完整详情

危险因素

  • benign prostatic hyperplasia (BPH)
  • constipation
  • medication (anticholinergic agents, opioid analgesics, alpha receptor agonists)
  • urolithiasis (ureteric calculi)
  • spinal cord injury, Parkinson disease, or multiple sclerosis
  • malignancy
  • pregnancy
  • hematuria
  • posterior urethral valves
  • bladder hernia
  • cystocele
  • iatrogenic injury
  • urethral instrumentation
  • retroperitoneal fibrosis
  • meatal stenosis
完整详情

诊断性检查

首要检查

  • urinary dipstick
  • renal ultrasound
  • serum BUN and creatinine
  • CBC
  • CT abdomen and pelvis without contrast
完整详情

需考虑的检查

  • urine culture
  • blood culture
  • CT scan abdomen and pelvis without and with contrast
  • magnetic resonance urography (MRU)
  • intravenous pyelogram (excretory urography)
  • nuclear renography (triple renal/MAG3 scan)
  • voiding cystourethrogram
  • bladder ultrasound
  • prostate specific antigen
  • tumor markers (e.g., serum carcinoembryonic antigen [CEA], CA125)
完整详情

治疗流程

初步治疗

unilateral or bilateral obstruction with signs of infection

急症处理

unilateral or bilateral obstruction due to calculi without signs of infection

unilateral obstruction not due to calculi without signs of infection

bilateral obstruction not due to calculi without signs of infection

撰稿人

作者

Harris E. Foster Jr., MD

Professor of Urology

Section Chief of Lower Urinary Tract Dysfunction and Reconstruction

Yale School of Medicine

New Haven

CT

利益声明

HEF declares that he has no competing interests.

Adam Benjamin Hittelman, MD, PhD

Associate Professor in Urology

Section Chief of Pediatric Urology

Yale School of Medicine

New Haven

CT

利益声明

ABH declares that he has provided expert testimony and has given lectures on obstructive uropathy.

Parth M. Patel, MD

Assistant Professor of Urology

Department of Urology

University of California Los Angeles

Los Angeles

CA

利益声明

PMP declares that he has no competing interests.

鸣谢

Harris E. Foster Jr., Adam Benjamin Hittelman, and Parth M. Patel would like to gratefully acknowledge Adrienne J. Carmack, a previous contributor to this topic.

利益声明

AJC declares that she has no competing interests.

同行评议者

Brian Cohen, MD

Private Practice Urologist

Asheville

NC

Declarações

BC declares that he has no competing interests.

Yekutiel Sandman, MD

Private Practice Urologist

Miami

FL

Declarações

YS declares that he has no competing interests.

Vincent Gnanapragasam, MBBS, BMedSci, PhD, FRCSEng, FRCSEd(Urol)

Lecturer in Uro-oncology and Consultant Urological Surgeon

Department of Urology

Addenbrooke's Hospital

Cambridge

UK

Declarações

VG declares that he has no competing interests.

Créditos aos pareceristas

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Referências

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Principais artigos

Wessells H, Morey A, Souter L, et al. Urethral stricture disease guideline amendment (2023). J Urol. 2023 Jul;210(1):64-71.Texto completo  Resumo

American College of Radiology. ACR appropriateness criteria: acute onset flank pain-suspicion of stone disease (urolithiasis)​. 2023 [internet publication].Texto completo

Sandhu JS, Bixler BR, Dahm P, et al. Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH): AUA guideline amendment 2023. J Urol. 2024 Jan;211(1):11-19.Texto completo  Resumo

European Association of Urology. EAU guidelines on urolithiasis. 2024 [internet publication].Texto completo

American Urological Association; Endourological Society. Surgical management of stones: AUA/Endourology Society guideline. 2016 [internet publication].Texto completo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
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