შეჯამება
განსაზღვრება
ანამნეზი და გასინჯვა
ძირითადი დიაგნოსტიკური ფაქტორები
- milk, egg, nut, fish, shellfish, wheat, or soy ingestion
- reproducible symptoms
- flushing, urticaria, or angioedema of the skin
- sneezing, rhinorrhea, or nasal congestion
- dyspnea, tachypnea, wheezing, coughing, or cyanosis
- hoarseness, stridor, or sense of choking
- nausea and vomiting
- abdominal cramping or bloating
- diarrhea
- conjunctival injection or lacrimation
- periorbital edema
- abrupt onset of symptoms
- reaction caused by small amount of food
- presence of other allergic disease
- laryngeal edema
სხვა დიაგნოსტიკური ფაქტორები
- tachycardia or bradycardia
- reaction exacerbated by exercise or exertion
- alcohol or medication ingestion before reaction
- cardiac arrhythmia
- hypotension
რისკფაქტორები
- family history of food allergy
- atopic dermatitis
- newborn
- perinatal peanut oil exposure
დიაგნოსტიკური კვლევები
1-ად შესაკვეთი გამოკვლევები
- in vitro IgE-specific immunoassay
- skin prick testing
Tests to avoid
- IgG testing
გასათვალისწინებელი კვლევები
- food challenges
- component-resolved diagnostics
მკურნალობის ალგორითმი
anaphylactic reaction
cutaneous symptoms
bronchospasm
rhinoconjunctivitis
following stabilization
კონტრიბუტორები
ავტორები
A. Wesley Burks, MD
Curnen Distinguished Professor and Chair
Department of Pediatrics
University of North Carolina
Chapel Hill
NC
გაფრთხილება:
AWB receives grant support to his institution from the National Institutes of Health and the Burroughs Wellcome Fund; royalties from UpToDate, Elsevier, and Walter Kluwer; consulting honorariums from Astella Pharma Global Development, Allergy Therapeutics (UK) Ltd, DBV Technologies, Kaléo, N-Fold, LLC, ALK-Abelló Inc, and UKKO Inc, as well as Aimmune Therapeutics, Consortia TX Inc, and Prota Therapeutics for his service on their respective scientific advisory boards. AWB owns stock in Allertein and Mastcell Pharmaceuticals. These interests do not directly relate to this topic but are being shared for full disclosure. AWB is an author of several references cited in this topic.
J. Andrew Bird, MD
Associate Professor
Department of Pediatrics
Division of Allergy and Immunology
University of Texas Southwestern Medical Center
Dallas
TX
გაფრთხილება:
JAB consults for AllerGenis, Allergy Therapeutics Ltd, Before Brands, DBV Technologies, Genentech, and Novartis. He receives grant funding to his institution from Aimmune, DBV Technologies, Genentech, HIH-NIAD, Novartic, Siolta, and Regeneron. JAB is the author of one reference cited in this topic.
რეცენზენტები
Justin Skripak, MD
Assistant Professor of Pediatric Allergy and Immunology
Mount Sinai School of Medicine
New York
NY
გაფრთხილება:
JS declares that he has no competing interests.
Hugh A. Sampson, MD
Professor of Pediatrics
Mount Sinai School of Medicine
New York
NY
გაფრთხილება:
HAS holds a 4% interest in a biotech company, Allertein Pharmaceuticals LLC, which is developing an engineered recombinant protein vaccine for peanut allergy, and 45% interest in a virtual company, Herbal Springs LLC, that holds a patent application on a herbal product for treating asthma and another for treating food allergy. HAS is an author of several references cited in this topic.
Adam Fox, MA(Hons) Cantab., MSc, MBBS, DCH, FRCPCH, FHEA, Dip. Allergy
Consultant and Honorary Senior Lecturer in Paediatric Allergy
Evelina Children's Hospital
Guy's & St Thomas' Hospitals NHS Foundation Trust
London
UK
გაფრთხილება:
AF declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
წყაროები
ძირითადი სტატიები
Chafen JJ, Newberry SJ, Riedl MA, et al. Diagnosing and managing common food allergies: a systematic review. JAMA. 2010 May 12;303(18):1848-56. აბსტრაქტი
Sicherer SH, Sampson HA. Food allergy: recent advances in pathophysiology and treatment. Annu Rev Med. 2009 Feb;60:261-77. აბსტრაქტი
Greer FR, Sicherer SH, Burks AW, et al. The effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, hydrolyzed formulas, and timing of introduction of allergenic complementary foods. Pediatrics. 2019 Apr;143(4):e20190281.სრული ტექსტი აბსტრაქტი
Muraro A, Halken S, Arshad SH, et al. EAACI food allergy and anaphylaxis guidelines: primary prevention of food allergy. Allergy. 2014 May;69(5):590-601.სრული ტექსტი აბსტრაქტი
Sampson HA, Gerth van Wijk R, Bindslev-Jensen C, et al. Standardizing double-blind, placebo-controlled oral food challenges: American Academy of Allergy, Asthma & Immunology-European Academy of Allergy and Clinical Immunology PRACTALL consensus report. J Allergy Clin Immunol. 2012 Dec;130(6):1260-74.სრული ტექსტი აბსტრაქტი
Heyman MB. American Academy of Pediatrics, Committee on Nutrition. Lactose intolerance in infants, children, and adolescents. Pediatrics. 2006 Sep;118(3):1279-86.სრული ტექსტი აბსტრაქტი
გამოყენებული სტატიები
ამ თემაში მოხსენიებული წყაროების სრული სია ხელმისაწვდომია მომხმარებლებისთვის, რომლებსაც აქვთ წვდომა BMJ Best Practice-ის ყველა ნაწილზე.
დიფერენციული დიაგნოზები
- Atopic dermatitis
- Urticaria
- Auriculotemporal syndrome
მეტი დიფერენციული დიაგნოზებიგაიდლაინები
- Diagnosis and management of celiac disease
- Anaphylaxis - a 2023 practice parameter update
მეტი გაიდლაინებიპაციენტის ბროშურები
Food allergy: what is it?
Food allergy: what treatments are available?
მეტი პაციენტის ბროშურები
შედით სისტემაში ან გამოიწერეთ BMJ Best Practice
ამ მასალის გამოყენება ექვემდებარება ჩვენს განცხადებას