Last reviewed: 30 Oct 2020
Last updated: 30 Jul 2020

Summary

Definition

History and exam

Key diagnostic factors

  • recurrent history of lesions following ultraviolet radiation exposure
  • young women and adolescents
  • family history of PLEĀ 
  • severe itching
  • reduced symptoms over the course of a year
  • erythematous patches
  • papules
  • plaques
  • vesicles

Risk factors

  • ultraviolet A exposure
  • oxidative stress/reactive oxygen species
  • family history of PLEĀ 
  • female sex

Diagnostic investigations

Investigations to consider

  • phototesting and photoprovocation
  • skin biopsy
More investigations to consider

Treatment algorithm

Contributors

Dermatology Registrar

St Mary's Hospital

London

UK

Disclosures

MS has been reimbursed by Vichy and La Roche Posay for presenting video clips and attending conferences about skin disease.

Consultant Dermatologist

Charing Cross/Hammersmith Hospital

Imperial College Hospitals NHS Trust

London

UK

Disclosures

SZ has received honoraria for speaking at, facilitating and/or attending meetings/advisory boards from L'Oreal, AbbVie, and Eli Lilly, and has had expenses sponsored for attending meetings by Leo, Novartis, L'Oreal and Naos.

Dr Mieran Sethi and Dr Shirin Zaheri would like to gratefully acknowledge Dr Catherine Hardman, Dr Sarah Hogan and Dr Ina Marion Hadshiew, previous contributors to this topic. CH, SH and IMH declare that they have no competing interests.

Peer reviewersVIEW ALL

Professor and Chair

Department of Dermatology

Stadtische Kliniken

Oldenburg

Germany

Disclosures

EH declares that he has no competing interests.

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