May occur as a primary process with no underlying dermatosis or as a secondary process due to an underlying pruritic dermatosis (such as atopic dermatitis or allergic contact dermatitis) or a systemic condition causing pruritus.
Underlying psychological comorbidities may be present including depression, anxiety disorder, or obsessive-compulsive disorder.
A difficult to manage and often recurring condition that is treated with potent topical corticosteroids and sedating antihistamines.
Lichen simplex chronicus (LSC) is a common cutaneous disorder characterized by well-circumscribed erythematous, often hyperpigmented, patches and plaques of thickened lichenified skin most commonly occurring on the neck, ankles, scalp, pubis, vulva, scrotum, and extensor forearms, as a result of chronic rubbing and scratching. 
Clinical Associate Professor
University of Iowa Departments of Dermatology and Pathology
Iowa City Veterans Affairs Medical Center
BLS declares that he has no competing interests.
Town Square Dermatology
HWW declares that he has no competing interests.
HG declares that she has no competing interests.
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