Lichen planus
小结
定义
病史和体格检查
关键诊断因素
- pruritus
- violaceous, flat-topped papules or plaques
- Wickham striae
- mucosal erosions and lacy white network
- scarring alopecia
- nail involvement
其他诊断因素
- dorsal pterygium
- history of hepatitis C (HCV)
危险因素
- hepatitis C (in some patient populations)
- -308 G/A polymorphism in TNF-alpha gene
- hepatitis B vaccination
- influenza vaccination
- coronavirus disease 2019 (COVID-19) vaccination
- psychosocial stress
- oral allergens
- use of certain drugs
诊断性检查
首要检查
- clinical diagnosis
需考虑的检查
- histopathology
- hepatitis C screen
- immunofluorescence
治疗流程
cutaneous disease
scalp disease
oral disease
genital disease
nail disease
撰稿人
作者
Deepani Munidasa, MBBS, MD
Consultant Dermatologist
Department of Dermatology
Anuradhapura Teaching Hospital
Anuradhapura
Sri Lanka
利益声明
DM declares that she has no competing interests.
鸣谢
Dr Deepani Munidasa would like to gratefully acknowledge Dr Susan Cooper, Dr Rebecca Dunn, Dr Julia S. Lehman, Dr Megha M. Tollefson, and Dr Lawrence E. Gibson, previous contributors to this topic.
利益声明
SC is chair of the British Society for the Study of Vulval Disease and receives royalties for contributions to UpToDate. RD, JSL, MMT, and LEG declare that they have no competing interests.
同行评议者
Brian Swick, MD
Clinical Assistant Professor
University of Iowa College of Medicine
Iowa City
IA
利益声明
BS declares that he has no competing interests.
David Cassarino, MD, PhD
Assistant Professor
Department of Pathology and Laboratory Medicine
University of California
Los Angeles
CA
利益声明
DC declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
参考文献
关键文献
American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].全文 摘要
Edwards SK, Bates CM, Lewis F, et al. 2014 UK national guideline on the management of vulval conditions. Int J STD AIDS. 2015 Aug;26(9):611-24. 摘要
Ioannides D, Vakirlis E, Kemeny L, et al. European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2020 Jul;34(7):1403-14.全文 摘要
参考文献
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
鉴别诊断
- Lichen simplex chronicus
- Psoriasis
- Lichen planus pemphigoides
更多 鉴别诊断指南
- Diagnosis and management of vulvar skin disorders
- European S1 guidelines on the management of lichen planus
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