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Granuloma annulare

Última revisão: 10 Jun 2025
Última atualização: 26 Nov 2020

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • asymptomatic grouped annular pink or flesh-coloured dermal papules
Detalhes completos

Outros fatores diagnósticos

  • flesh-coloured, pink, or brown macules or small papules
  • soft-tissue nodules
  • perforating papules, crusting or ulcerated lesions
  • erythematous patches
Detalhes completos

Fatores de risco

  • diabetes mellitus
  • haematological malignancy
  • herpes zoster
  • HIV
  • hepatitis
  • hyperlipidaemia
  • thyroid disease
  • medications
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • clinical diagnosis
Detalhes completos

Investigações a serem consideradas

  • skin biopsy
  • fasting blood sugar
  • thyroid function tests
  • lipid screening
  • hepatitis screen
  • HIV testing
Detalhes completos

Algoritmo de tratamento

AGUDA

localised variant (classic annular rash)

generalised variant (widespread macular rash)

perforating variant (crusted or ulcerated lesion)

subcutaneous variant (soft nodule)

patch variant (erythematous plaques)

Colaboradores

Autores

Misha Rosenbach, MD

Associate Professor

Dermatology and Internal Medicine

University of Pennsylvania

Philadelphia

PA

Declarações

MR has received consulting fees from Merck, aTyr Pharma, and Processa Pharma, not related to granuloma annulare. He has received grant support from Processa Pharma, not related to granuloma annulare. MR has received salary support from the AMA/JAMA for his role at JAMA Dermatology as Deputy Editor. MR is an author of references cited in this topic.

Agradecimentos

Dr Misha Rosenbach would like to gratefully acknowledge Dr Susmita Mukherjee, a previous contributor to this topic. SM declares that she has no competing interests.

Revisores

Aisha Sethi, MD

Assistant Professor of Medicine

Associate Residency Program Director

University of Chicago

Chicago

IL

Declarações

AS declares that she has no competing interests.

Robert Herd, MSc, MD, FRCP

Consultant Dermatologist

Department of Dermatology

Nuffield Hospital

Glasgow

UK

Declarações

RH declares that he has no competing interests.

Brenda L. Pellicane, MD

Dermatologist

Wayne State University School of Medicine

Department of Dermatology

Detroit

MI

Declarações

BLP declares that she has no competing interests.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

Piette EW, Rosenbach M. Granuloma annulare: clinical and histologic variants, epidemiology, and genetics. J Am Acad Dermatol. 2016 Sep;75(3):457-65. Resumo

Thornsberry LA, English JC 3rd. Etiology, diagnosis, and therapeutic management of granuloma annulare: an update. Am J Clin Dermatol. 2013 Aug;14(4):279-90. Resumo

Piette EW, Rosenbach M. Granuloma annulare: pathogenesis, disease associations and triggers, and therapeutic options. J Am Acad Dermatol. 2016 Sep;75(3):467-79. Resumo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.

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