A bacterial respiratory pathogen that is a frequent cause of community-acquired pneumonia in children and adults.
An obligate intracellular parasite that can only be isolated in tissue culture, although culture is not widely available.
Pneumonia due to Chlamydia pneumoniae cannot be differentiated clinically from pneumonia due to other atypical organisms, especially Mycoplasma pneumoniae .
Serologic diagnosis is complicated by the requirement for paired sera and the lack of FDA-approved serologic assays.
Treatment with macrolides, quinolones, or tetracyclines appears to be equally efficacious.
Chlamydia pneumoniae (an obligate intracellular bacterium) is a frequent respiratory pathogen in humans that occurs worldwide and in all age groups. It is a major cause of community-acquired pneumonia. Reliable diagnosis of respiratory infection due to C pneumoniae and investigation of its role in chronic diseases remain difficult due to the absence of well-standardized and commercially available diagnostic tests. 
Professor of Pediatrics and Medicine
Division of Pediatric Infectious Diseases
SUNY Downstate Medical Center
MRH is an author of a number of references cited in this monograph.
Associate Professor of Clinical Medicine
Division of Pulmonary/Critical Care Medicine
School of Medicine
University of Missouri-Columbia
YO declares that he has no competing interests.
Professor of Respiratory Medicine
Honorary Consultant Physician in Allergy and Respiratory Medicine
Department of Respiratory Medicine
Imperial College School of Medicine
SJ has received fees for speaking, and research and consultant fees from Sanofi Pasteur, Aventis, GlaxoSmithKline, AstroZeneca, Merck, Pfizer, Centocor, and Synergen.
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