Last reviewed: 24 Jun 2021
Last updated: 01 Dec 2020
Summary
Definition
History and exam
Key diagnostic factors
- pain on swallowing
- fever (>100.5°F [>38°C])
- tonsillar exudate
Other diagnostic factors
- sudden onset of sore throat
- headache
- abdominal pain
- nausea and vomiting
- presence of cough or runny nose
- tonsillar erythema
- tonsillar enlargement
- enlarged anterior cervical lymph nodes
Risk factors
- age between 5 and 15 years
- contact with infected people in enclosed spaces (e.g., child care centers, schools, prison)
Diagnostic investigations
1st investigations to order
- throat culture
- rapid streptococcal antigen test
Investigations to consider
- serologic testing for streptococci
- WBC count and differential
- heterophile antibodies
- vaginal and cervical, or penile, and rectal cultures
- HIV viral load assay
- lateral cervical view x-ray, exposed for soft tissue
Treatment algorithm
Contributors
Authors
Christos Georgalas, PhD, DLO, FRCS (ORL-HNS)
Professor of Surgery - Head and Neck
University of Nicosia
Cyprus
Disclosures
CG declares that he has no competing interests.
Eleftherios Margaritis, PhD, MSc, MD
Otolaryngologist - Head and Neck Surgeon
Collaborator in Otolaryngology
ENT Department
Hippokration University Hospital
Athens
Greece
Disclosures
EM declares that he has no competing interests.
Peer reviewers
Itzhak Brook, MD, MSc
Professor of Pediatrics and Medicine
Georgetown University
Washington
DC
Disclosures
IB declares that he has no competing interests.
Chris Del Mar, MB BChir, FRACGP MD, MA, FAFPHM
Dean
Faculty of Health Sciences and Medicine
Bond University
Gold Coast
Queensland
Australia
Disclosures
CDM is an author of a number of references cited in this topic.
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