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Febrile seizure

Последний просмотренный: 17 Jan 2026
Last updated: 19 Jul 2022

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • presence of risk factors
  • febrile illness
  • seizure
Полная информация

Другие диагностические факторы

  • normal postictal exam
Полная информация

Факторы риска

  • temperature elevation
  • young age
  • male sex
  • family history of febrile seizures
  • viral or bacterial infection outside the central nervous system
  • vaccinations
  • antenatal exposure to nicotine
  • iron deficiency
  • complications of pregnancy, labour, and delivery
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • diagnosis is clinical
Полная информация

Исследования, проведение которых нужно рассмотреть

  • lumbar puncture
  • viral studies
  • blood culture
  • EEG
  • brain MRI
  • serum sodium
  • FBC
  • capillary blood gluscose
  • serum glucose
  • iron studies
Полная информация

Алгоритм лечения

Начальные

febrile status epilepticus

Острый

first simple febrile seizure

first complex seizure

ПРОДОЛЖЕНИЕ

febrile illness with prior history of simple seizure or 1 complex seizure

history of 2 or more complex febrile seizures with ineffective diazepam treatment

Составители

Авторы

Damian Roland, BMedSci, MBBS, FRCPCH, PhD

Honorary Associate Professor and Consultant in Paediatric Emergency Medicine

Paediatric Emergency Medicine Leicester Academic (PEMLA) Group

Children’s Emergency Department

Leicester Royal Infirmary

Leicester

UK

Declarações

DR declares that he is a previous member of the National Institute for Health and Care Excellence Feverish Illness in Children Guideline Group.

Agradecimentos

Dr Damian Roland would like to gratefully acknowledge Dr Leena Mewasingh, Dr Frances Morrison, Dr John J. Millichap and Dr J. Gordon Millichap, previous contributors to this topic. LM has received funding from drug companies (e.g., Eisai) to attend medical conferences and been invited to an educational symposium (Novartis, LivaNova). FM declares that she has no competing interests. JJM serves as an Associate Editor of Neurology and serves on the editorial board of Pediatric Neurology Briefs; volunteers on the medical advisory board of The Jack Pribaz Foundation (KCNQ2.org); received speaker honoraria from Invitae; received royalties for online monographs from Up-To-Date; served on the scientific advisory board for Mallinckrodt; is principal investigator for a clinical trial funded by UCB Pharma; and is the principal investigator for research grants from Citizens United for Research in Epilepsy and the Thrasher Research Fund. JJM is an author of a number of references cited in this topic. JGM is an author of a number of references cited in this topic.

Revisores

Robert S. Rust, Jr., MA, MD

Professor

Department of Neurology

University of Virginia Health System

Charlottesville

VA

Declarações

RSR declares that he has no competing interests.

Créditos aos pareceristas

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Referências

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Principais artigos

American Academy of Pediatrics: Subcommittee on Febrile Seizures. Clinical practice guideline: neurodiagnostic evaluation of the child with a simple febrile seizure. Pediatrics. 2011 Feb;127(2):389-94.Texto completo  Resumo

American Academy of Pediatrics. Febrile seizures: clinical practice guideline for the long-term management of the child with simple febrile seizures. Pediatrics. 2008 Jun;121(6):1281-6.Texto completo  Resumo

Natsume J, Hamano SI, Iyoda K, et al. New guidelines for management of febrile seizures in Japan. Brain Dev. 2017 Jan;39(1):2-9. Resumo

Offringa M, Newton R, Nevitt SJ, et al. Prophylactic drug management for febrile seizures in children. Cochrane Database Syst Rev. 2021 Jun 16;(6):CD003031.Texto completo  Resumo

Wilmshurst JM, Gaillard WD, Vinayan KP, et al. Summary of recommendations for the management of infantile seizures: task force report for the ILAE Commission of Pediatrics. Epilepsia. 2015 Aug;56(8):1185-97.Texto completo  Resumo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
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