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High altitude illness

Последний просмотренный: 19 Aug 2025
Last updated: 26 Oct 2023

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • headache
  • ataxia
  • change in mental state: for example, tired, irritable, confused, forgetful, irrational
  • abnormal tone, power, and reflexes
Полная информация

Другие диагностические факторы

  • nausea, vomiting, and loss of appetite
  • fatigue and weakness
  • dizziness or lightheadedness
  • difficulty sleeping
  • visual disturbance
  • shortness of breath
  • cough with or without sputum
  • rales
  • peripheral edema
  • accentuated pulmonary second sound
  • pyrexia
  • elevated respiratory rate
  • elevated heart rate
  • low arterial oxygen saturation
  • cyanosis
  • urinary incontinence or retention
  • retinal hemorrhages and papilledema on fundoscopy
  • chest pain
  • cranial nerve palsies (III, IV, and VI)
  • visual and auditory hallucinations, seizures, tinnitus, vertigo, tremors, speech disturbance, and deafness
Полная информация

Факторы риска

  • high altitude
  • rapid ascent
  • low-altitude residence
  • history of previous altitude illness
  • younger age
  • exertion
  • poor awareness of high-altitude illness prior to travel
  • existing medical condition
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • clinical diagnosis
Полная информация

Исследования, проведение которых нужно рассмотреть

  • arterial blood gases
  • chest radiography
  • ECG
  • chest ultrasound and echocardiography
  • WBC count
  • lumbar puncture
  • CT head
  • MRI head
Полная информация

Алгоритм лечения

Начальные

high-altitude ascent planned

Острый

AMS

HAPE only

HACE only

concurrent HAPE and HACE

Составители

Авторы

Jeremy S. Windsor, MBChB, DCH, FCARCSI

Specialist Registrar

Anaesthetics and Intensive Care Medicine

University College Hospital

London

UK

Раскрытие информации

JSW is an author of a number of references cited in this topic.

Рецензенты

James S. Milledge, MBBS

Honorary Professor

Department of Physiology

University College London

London

UK

Раскрытие информации

JSM declares that he has no competing interests.

Mike Grocott, MD

Senior Lecturer

Intensive Care Medicine

University College Hospital

London

UK

Раскрытие информации

MG declares that he has no competing interests.

Haibo Wang, MD, PhD

Assistant Professor

LSU Health Sciences Center

Shreveport

LA

Раскрытие информации

HW declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel. Section 4: environmental hazards & risks - high elevation travel & altitude illness. May 2023 [internet publication].Полный текст

Roach RC, Hackett PH, Oelz O, et al. The 2018 lake louise acute mountain sickness score. High Alt Med Biol. 2018 Mar;19(1):4-6.Полный текст  Аннотация

Luks AM, Auerbach PS, Freer L, et al. Wilderness medical society clinical practice guidelines for the prevention and treatment of acute altitude illness: 2019 update. Wilderness Environ Med. 2019 Dec;30(4s):S3-18.Полный текст  Аннотация

Donegani E, Paal P, Küpper T, et al. Drug use and misuse in the mountains: a UIAA MedCom consensus guide for medical professionals. High Alt Med Biol. 2016 Sep;17(3):157-84. Аннотация

Ritchie ND, Baggott AV, Andrew Todd WT. Acetazolamide for the prevention of acute mountain sickness - a systematic review and meta-analysis. J Travel Med. 2012 Sep-Oct;19(5):298-307.Полный текст  Аннотация

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • High altitude illness images
  • Отличия

    • Asthma, acute exacerbation
    • Community-acquired pneumonia
    • Acute exacerbation of chronic heart failure (CHF)
    Больше Отличия
  • Guidelines

    • CDC Yellow Book: health information for international travel - high elevation travel & altitude illness
    • Wilderness Medical Society practice guidelines for the prevention and treatment of acute altitude illness: 2019 update​
    Больше Guidelines
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