Summary
Definition
History and exam
Other diagnostic factors
- cervical discharge
- friable cervix
- abnormal vaginal bleeding
- penile discharge
- vaginal discharge
- dysuria
- pelvic pain
- fever/chills
- nausea/vomiting
- scrotal pain
- myalgias
- abdominal pain
- mucopurulent rectal discharge or tenesmus
Risk factors
- age under 25 years, sexually active
- new sex partner or multiple sex partners
- sexual activity with infected partner
- condoms not used
- history of prior STI
- ethnicity
- urban residence and low socioeconomic status
Diagnostic investigations
Investigations to consider
- direct immunofluorescence
- enzyme immunoassay
- nucleic acid hybridization tests
- cell culture
Treatment algorithm
Contributors
Authors
Professor of Medicine
Johns Hopkins University School of Medicine
Baltimore
MD
Disclosures
AR declares that she has no competing interests.
Dr Anne Rompalo would like to gratefully acknowledge Dr Christopher K. Fairley, a previous contributor to this topic.
Disclosures
CKF declares that he has no competing interests.
Peer reviewers
Assistant Editor
American Family Physician
Clinical Assistant Professor
GUSOM Medical Officer
US Preventive Services Task Force
Disclosures
KL declares that he has no competing interests.
Professor/Head
Department of Infectious Diseases
Aarhus University Hospital
Skejby Sygehus
Aarhus
Denmark
Disclosures
LJO has been funded by Pfizer to write a leaflet on Chlamydia infections.
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