Last reviewed: June 2019
Last updated: April  2019

Summary

Differentials

Common

  • Alcoholic liver disease
  • Choledocholithiasis
  • Hepatitis E
  • Hepatitis A
  • Hepatitis B
  • Hepatitis C
  • Nonalcoholic steatohepatitis
  • Drug-induced direct hyperbilirubinemia
  • Ascending cholangitis
  • Autoimmune hepatitis
  • Pancreatic carcinoma
  • Hemochromatosis
  • Pregnancy
  • Postoperative stricture
  • Drug-induced indirect hyperbilirubinemia
  • Hemolytic anemia
  • Gilbert syndrome

Uncommon

  • Hepatitis D
  • Immunoglobulin G4 (IgG4) cholangiopathy
  • Cholangiocarcinoma
  • Primary biliary cholangitis
  • Primary sclerosing cholangitis
  • Wilson disease
  • Alpha-1 antitrypsin deficiency
  • Parasitic infections
  • AIDS cholangiopathy
  • Crigler-Najjar syndrome, types 1 and 2
  • Biliary atresia
  • Carotenemia

Contributors

Authors VIEW ALL

Consultant Gastroenterologist and Associate Lecturer in Medicine

University of the West Indies

Department of Medicine

San Fernando General Hospital

San Fernando

Trinidad

West Indies

Disclosures

RR declares that he has no competing interests.

Dr Rene Ramnarace would like to gratefully acknowledge Dr Harry R. Dalton, Dr Peter Draganov, and Dr Grant F. Hutchins, previous contributors to this topic.

Peer reviewers VIEW ALL

Associate Professor of Surgery

Division of General Pediatric Surgery; Director of the Trauma Program

Childrens Hospital

Los Angeles

CA

Disclosures

JSU declares that he has no competing interests.

Consultant

Laparoscopic Upper Gastrointestinal Surgeon

Derriford Hospital

Plymouth

UK

Disclosures

GS declares that he has no competing interests.

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