Last reviewed: 20 Sep 2021
Last updated: 17 Aug 2021

Summary

Differentials

Common

  • Bacterial vaginosis
  • Trichomoniasis
  • Vulvovaginal candidiasis
  • Chlamydia trachomatis infection
  • Neisseria gonorrhoeae infection
  • Mycoplasma genitalium
  • Irritant and allergic vaginitis
  • Physiological leukorrhea in adults
  • Foreign body in children
  • Nonspecific vaginitis
  • Physiological leukorrhea in children

Uncommon

  • Herpes simplex virus (HSV) infection
  • Streptococcal vaginitis in adults
  • Genital schistosomiasis
  • Entamoeba gingivalis plus intrauterine device (IUD)
  • Inadequate hygiene
  • Foreign body in adults
  • Contraceptive vaginal ring-related
  • Atrophic vaginitis
  • Postpuerperal atrophic vaginitis; lochia
  • Behcet syndrome
  • Desquamative inflammatory vaginitis
  • Erosive lichen planus
  • Postsurgical
  • Postradiation
  • Cervical cancer
  • Carcinoma of the fallopian tube
  • Pinworm infection
  • Streptococcal vaginitis in children
  • Sexual abuse
  • Transmitted maternal birth canal infection
  • Prolapsing fibroid
  • Vaginal fistula
  • Lymphoma of genital tract

Contributors

Authors

Jenell S. Coleman, MD, MPH, FACOG

Associate Professor

Division Director, Gynecologic Specialties

Medical Director, JHOC Women’s Health Center

Director, JHOC Resident Continuity Clinic

Co-Director, JHOC Colposcopy Clinic

Department of Gynecology & Obstetrics

Johns Hopkins University School of Medicine

Baltimore

MD

Disclosures

JC is an author of a reference cited in this topic.

Acknowledgements

Dr Jenell Coleman would like to gratefully acknowledge Dr Veronica Gomez-Lobo and Dr Isabelle Guichard, previous contributors to this topic. VGL and IG declare that they have no competing interests.

Peer reviewers

David Chelmow, MD

Chair

Department of Obstetrics and Gynecology

Virginia Commonwealth University

Richmond

VA

Disclosures

DC declares that he has no competing interests.

Lesley Bacon, FFSRH, MRCGP

Consultant in Sexual and Reproductive Health

Lewisham Primary Care Trust

Waldron Health Centre

London

UK

Disclosures

LB was a member of the group that produced the 2006 Faculty of Sexual and Reproductive Health guidance on the management of women with vaginal discharge presenting in non-GU setting.

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