Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- corona phlebectatica (malleolar flare or ankle flare)
- ankle swelling
- hyperpigmentation (brawny oedema)
- lipodermatosclerosis
- atrophie blanche
- leg ulcers
Other diagnostic factors
- leg fatigue, aching, and/or discomfort
- heavy legs
- leg cramps
- telangiectasias
- reticular veins
- dilated tortuous veins
- dry and scaly skin
- skin burning and itching
- unilateral leg swelling
Risk factors
- increasing age
- family history
- smoking
- deep vein thrombosis
- orthostatic occupation
- female sex
- obesity (waist circumference)
- ligamentous laxity
Diagnostic investigations
1st investigations to order
- duplex ultrasound
Investigations to consider
- ascending phlebography
- CT venography
- magnetic resonance venography
- CT abdomen and pelvis
- abdomen and pelvis ultrasound
- intravascular ultrasound
- air plethysmography
Treatment algorithm
all symptomatic patients
Contributors
Authors
Joseph L. Mills Sr, MD
Professor and Chief
Division of Vascular Surgery and Endovascular Therapy
Michael E. DeBakey Department of Surgery
Baylor College of Medicine
Houston
TX
Disclosures
JLM declares that he has no competing interests.
David G. Armstrong, DPM, MD, PhD
Professor of Surgery
Director of Southwestern Academic Limb Salvage Alliance (SALSA)
Keck School of Medicine of University of Southern California (USC)
Los Angeles
CA
Disclosures
DGA declares that his work is partially supported by grants from the National Institutes of Health and the National Institute of Diabetes and Digestive and Kidney Diseases.
Peer reviewers
Anahita Dua, MD, MS, MBA, FACS
Assistant Professor of Surgery
Massachusetts General Hospital/Harvard Medical School
Boston
MA
Disclosures
AD declares that she has no competing interests.
Paul Tisi, MBBS, MS, FRCSEd
Medical Director/Consultant Vascular Surgeon
Bedford Hospital
Bedford
UK
Disclosures
PT declares that he has no competing interests.
Differentials
- Diabetic foot ulcer
- Arterial ulcer
- Squamous cell carcinoma (Marjolin)
More DifferentialsGuidelines
- ACR appropriateness criteria® lower extremity chronic venous disease
- European Society for Vascular Surgery (ESVS) 2022 clinical practice guidelines on the management of chronic venous disease of the lower limbs
More GuidelinesPatient information
Dermatitis
Diabetes type 2: should I take insulin?
More Patient information- Log in or subscribe to access all of BMJ Best Practice
Use of this content is subject to our disclaimer