Evaluation of metabolic acidosis

Last reviewed: 10 Nov 2024
Last updated: 20 Nov 2024

Summary

Differentials

Common

  • GI loss of bicarbonate
  • Renal loss of bicarbonate - renal tubular acidosis type 1 and 2
  • Renal tubular acidosis type 4
  • Diabetic ketoacidosis
  • Alcohol ketoacidosis
  • Ingestion of toxic substances
  • Acetaminophen ingestion (5-oxoproline toxicity)
  • Salicylate intoxication
  • Lactic acidosis
  • Acute renal failure
  • Chronic renal failure
Full details

Uncommon

  • Addition of acid
Full details

Contributors

Authors

Dinkar Kaw, MD, FACP, FASN
Dinkar Kaw

Professor of Medicine

Division of Nephrology

Department of Medicine

University of Toledo College of Medicine and Life Sciences

Toledo

OH

Disclosures

DK declares that he has no competing interests.

Acknowledgements

Dr Dinkar Kaw would like to gratefully acknowledge Dr Joseph I. Shapiro, a previous contributor to this topic. JIS declares that he has no competing interests.

Peer reviewers

Tausif Zar, MD

Staff Nephrologist

Division of Nephrology

Department of Medicine

Southern Arizona Veterans Affairs Health Care System

Tucson

AZ

Disclosures

TZ declares that he has no competing interests.

Andrew Fenves, MD

Professor of Medicine

Baylor University Medical Center

Dallas

TX

Disclosures

AF declares that he has no competing interests.

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