Summary
Definition
History and exam
Risk factors
- advanced age
- male gender
- FHx
- cigarette smoking
- organic and inorganic dust exposure
- gastroesophageal reflux
- infection
- diabetes
Diagnostic investigations
Investigations to consider
- PFTs
- ANAs
- rheumatoid factor
- surgical lung biopsy
- bronchoalveolar lavage (BAL)
- transbronchial biopsy
Treatment algorithm
Contributors
Authors VIEW ALL
Assistant Professor of Clinical Medicine
Pulmonary, Allergy, and Critical Care Division
Perelman School of Medicine
University of Pennsylvania
Philadelphia
PA
Disclosures
JDF declares that he has no competing interests.
Associate Professor of Clinical Medicine
Pulmonary, Allergy, and Critical Care Division
Perelman School of Medicine
University of Pennsylvania
Philadelphia
PA
Disclosures
MEK has received research support for serving as a clinical trial site principal investigator from Gilead, MedImmune, Genentech, and Sanofi.
Dr Judd David Flesch and Dr Mary Elizabeth Kreider would like to gratefully acknowledge Dr Gregory Tino and Dr Jeffrey C. Munson, previous contributors to this topic. GT has served as a consultant for InterMune. GT has served as a principal investigator for clinical trials in idiopathic pulmonary fibrosis. JCM declares that he has no competing interests.
Peer reviewers VIEW ALL
Medical Director
Lung Transplant & Advanced Lung Disease Program
Inova Fairfax Hospital
Falls Church
VA
Disclosures
SN is an author of a reference cited in this monograph.
Professor of Respiratory Medicine
Interstitial Lung Disease Unit
Royal Brompton Hospital
London
UK
Disclosures
AW declares that he has no competing interests.
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