Patients with anorexia nervosa (AN) typically have low body weight, intense fear of gaining weight, and a body image disturbance.
While more often detected in women, cases of AN in young men may be under-represented.
Weight restoration with refeeding techniques is essential for prevention of sequelae, such as heart failure, fertility problems, and osteoporosis.
Patients with AN are often identified through family referral, pediatric monitoring of weight during routine physical exam, and the patient's physical complaints.
Early intervention is key in order to prevent long-term psychiatric and physical complications of AN.
Among psychiatric illnesses, AN has one of the highest premature mortality rates (with a risk of premature death of approximately 5-fold greater than that of peers).
Anorexia nervosa (AN) is an eating disorder characterized by restriction of caloric intake leading to low body weight, an intense fear of gaining weight, and a body image disturbance.
History and exam
Key diagnostic factors
- significantly low body weight
- fear of gaining weight or becoming fat, or behaviors that interfere with weight gain despite evidence of significantly low body weight
- disturbed body image
- calorie restriction
- binge-eating and/or purging
- misuse of laxatives, diuretics, or diet pills
- decreased subcutaneous fat
Other diagnostic factors
- general fatigue, weakness, and poor concentration
- significant preoccupation with thoughts of food
- orthostatic hypotension
- nonspecific gastrointestinal symptoms
- cardiac symptoms and signs
- changes to hair, skin, and nails
- dependent edema
- osteopenia or osteoporosis
- female sex
- adolescence and puberty
- obsessive and perfectionist traits
- exposure to Western media
- genetic influence
- middle and upper socioeconomic classes
1st investigations to order
- serum chemistry
- thyroid function tests
- liver function tests
Investigations to consider
- bone densitometry (dual-energy x-ray absorptiometry)
- estradiol in females
- testosterone in males
medically stable and suitable for outpatient treatment
medically unstable or outpatient failure
- Bulimia nervosa
- Avoidant-restrictive food intake disorder (ARFID)
- Practice guideline for the treatment of patients with eating disorders
- Guidelines for the management of eating disorders
Anorexia: questions to ask your doctorMore Patient leaflets
Body Mass Index (BMI) percentiles for boys (2 to 20 years)
Body Mass Index (BMI) percentiles for girls (2 to 20 years)More Calculators
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