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Laryngitis

Last reviewed: 1 Mar 2025
Last updated: 11 Mar 2025

Summary

Definition

History and exam

Key diagnostic factors

  • hoarseness
  • dysphagia
  • sore throat
  • odynophagia
  • cough
  • hyperemia of the oropharynx
  • history of heavy vocal use
  • gastroesophageal reflux
  • oropharyngeal white-gray exudates
Full details

Other diagnostic factors

  • rhinitis
  • fatigue and malaise
  • fever
  • enlarged tonsils
  • enlarged, tender anterior cervical lymph nodes
  • postnasal drip
  • dyspnea
  • weight loss
  • tonsillopharyngeal exudate
  • acute respiratory distress
  • toxic appearance
  • drooling
  • stridor
Full details

Risk factors

  • recent history of upper respiratory infection
  • incomplete or absent Haemophilus influenzae type B (Hib) vaccination
  • incomplete or absent diphtheria vaccination
  • contact with infected individual
  • travel to area where diphtheria or tuberculosis are endemic
  • HIV or other immunocompromise
  • use of inhaled corticosteroids or prolonged courses of antibiotics
  • heavy vocal use
  • tobacco use
Full details

Diagnostic tests

1st tests to order

  • laryngoscopy
Full details

Tests to avoid

  • computed tomography (CT)
  • magnetic resonance imaging (MRI)
  • viral panel testing
Full details

Tests to consider

  • biopsy
  • oropharyngeal cultures
  • nasal swab for culture
  • serum immunoprecipitation or polymerase chain reaction for diphtheria
  • complete blood count
  • rapid antigen detection test
  • chest x-ray
  • sputum cultures
  • videostroboscopy
Full details

Treatment algorithm

INITIAL

with potential airway compromise

ACUTE

viral

suspected bacterial: nondiphtheria and nontuberculous

confirmed diphtheria

tuberculosis

fungal

vocal strain

Contributors

Authors

Vaninder Kaur Dhillon, MD

Assistant Professor

Johns Hopkins University

Otolaryngology-Head and Neck Surgery

Divisions of Laryngology and Endocrine Head and Neck Surgery

Bethesda

MD

Disclosures

VKD declares that she has no competing interests.

Acknowledgements

Dr Vaninder Kaur Dhillon would like to gratefully acknowledge Dr Chad W. Whited, Dr Seth H. Dailey and Dr Ozlem E. Tulunay-Ugur, the previous contributors to this topic. CWW, SHD and OETU declare that they have no competing interests.

Peer reviewers

Michael Johns, MD

Director

Assistant Professor

Emory University

Atlanta

GA

Disclosures

MJ declares that he has no competing interests.

James Suen, MD

Chair; Professor

University of Arkansas for Medical Sciences

Department of Otolaryngology - Head and Neck Surgery

Little Rock

AR

Disclosures

JS declares that he has no competing interests.

Remco de Bree, MD, PhD

Otolaryngologist

Head and Neck Surgeon

VU University Medical Center

Amsterdam

The Netherlands

Disclosures

RdB declares that he has no competing interests.

  • Laryngitis images
  • Differentials

    • Tonsillitis
    • Infectious mononucleosis
    • Allergic rhinitis
    More Differentials
  • Guidelines

    • Clinical practice guideline: hoarseness (dysphonia)
    • Sore throat (acute): antimicrobial prescribing
    More Guidelines
  • Patient information

    Sore throat

    More Patient information
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