Summary
Definition
Анамнез и осмотр
Ключевые диагностические факторы
- target lesions of the extremities
- previous episode of EM
- mucosal erosions
Другие диагностические факторы
- targetoid lesions
- rapid onset of lesions
- self-limiting course
- clustered vesicles on an erythematous base
- rhonchi, rales, and/or wheezes
- red tympanic membranes
Факторы риска
- prior episode of erythema multiforme
- herpes simplex virus (HSV) infection
- certain other infections
- Mycoplasma pneumonia infection
- lymphoma
- Kawasaki disease
- use of certain medications
- vaccinations
- tattoos
Диагностические исследования
Исследования, которые показаны в первую очередь
- clinical diagnosis
Исследования, проведение которых нужно рассмотреть
- hematoxylin and eosin biopsy
- immunofluorescence biopsy
- CBC
- serum electrolytes
- herpes simplex virus (HSV) serology
- rapid polymerase chain reaction (PCR)
- cold-hemagglutination serology
- M pneumoniae titers
- CXR
- autoantibody titers
Неотложные исследования
- antidesmoplakin antibodies
Алгоритм лечения
EM minor
EM major
recurrent EM
Составители
Авторы
Nathan W. Rojek, MD, FAAD
Assistant Professor
Director, Inpatient Dermatology
Department of Dermatology
University of California, Irvine
Irvine
CA
Раскрытие информации
NWR declares that he has no competing interests.
Выражение благодарностей
Dr Nathan W. Rojek would like to gratefully acknowledge Dr Areta Kowal-Vern, Dr Jonathan Silverberg, and Dr Nanette Silverberg, the previous contributors to this topic.
Раскрытие информации
AK-V, JS, and NS declare that they have no competing interests.
Рецензенты
Cristine Radojicic, MD
Staff Physician
Cleveland Clinic
Cleveland
OH
Раскрытие информации
CR declares that she has no competing interests.
Brian Swick, MD
Clinical Assistant Professor
University of Iowa College of Medicine
Iowa City
IA
Раскрытие информации
BS declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Список литературы
Основные статьи
Lerch M, Mainetti C, Terziroli Beretta-Piccoli B, Harr T. Current perspectives on erythema multiforme. Clin Rev Allergy Immunol. 2018 Feb;54(1):177-84. Аннотация
Grünwald P, Mockenhaupt M, Panzer R, et al. Erythema multiforme, Stevens-Johnson syndrome/toxic epidermal necrolysis - diagnosis and treatment. J Dtsch Dermatol Ges. 2020 Jun;18(6):547-53. Аннотация
Soares A, Sokumbi O. Recent updates in the treatment of erythema multiforme. Medicina (Kaunas). 2021 Sep 1;57(9):921.Полный текст Аннотация
de Risi-Pugliese T, Sbidian E, Ingen-Housz-Oro S, et al. Interventions for erythema multiforme: a systematic review. J Eur Acad Dermatol Venereol. 2019 May;33(5):842-9. Аннотация
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Отличия
- Urticaria
- Polymorphous light eruption (PMLE)
- Subacute cutaneous lupus erythematosus
Больше ОтличияРекомендации
- Erythema multiforme
- Diagnosis and treatment of adults with community-acquired pneumonia
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