Ileus

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Last reviewed: 9 Apr 2025
Last updated: 18 Nov 2024

Summary

Definition

History and exam

Key diagnostic factors

  • nausea and vomiting
  • abdominal distention
  • no features of mechanical obstruction or peritoneal inflammation (e.g., abdominal hernia, peritoneal signs)
Full details

Other diagnostic factors

  • obstipation (severe constipation with no passage of stool or flatus)
  • discomfort and abdominal cramping
  • decreased or hypoactive bowel sounds
  • hypovolemia
Full details

Risk factors

  • abdominal surgery
  • acute/systemic illness (e.g., myocardial infarction, pneumonia, acute cholecystitis, pancreatitis, sepsis, multi-organ trauma)
  • nonabdominal surgery
  • electrolyte imbalance
  • opioid analgesics, anticholinergics, or anesthetic gases
  • comorbidities (e.g., diabetes mellitus, cardiovascular insufficiency, Chagas disease, scleroderma)
Full details

Diagnostic tests

1st tests to order

  • serum electrolytes
  • serum magnesium
  • CBC
  • abdomen and pelvis CT scan (with intravenous contrast and oral water soluble contrast)
Full details

Tests to consider

  • serum LFTs
  • serum amylase
  • serum lipase
  • small bowel series
  • gastric emptying study
Full details

Treatment algorithm

ACUTE

postoperative ileus

nonsurgical cause

ONGOING

ileus lasting longer than 3 days or prolonging the postoperative recovery

Contributors

Expert advisers

Steven D. Wexner, MD, PhD (Hon), FACS, FRCS (Eng), FRCS (Ed), FRCSI (Hon)

Director

Digestive Disease Center

Professor and Chair

Department of Colorectal Surgery

Cleveland Clinic

Weston

FL

Disclosures

SDW has received consulting fees, stock options, and royalties from the following companies. These relationships are ongoing. Consulting: ICON Language Services, Intuitive Surgical, Stryker, Medtronic, Takeda, ARC/Corvus, Astellas, Baxter, Olympus, AIS Channel, Livsmed. Royalties: Medtronic, Intuitive Surgical, Karl Storz Endoscopy-America, Unique Surgical Innovations. Stock Options: Regentys, LifeBond, Pragma/GibLib, and Renew Medical.

Sameh Hany Emile Rizkalla, MBBCh, MSc, MD, FACS

Research associate, Colorectal Surgery Department

Digestive Disease Center

Professor and Chair

Department of Colorectal Surgery

Cleveland Clinic

Weston

FL

Disclosures

SHER declares that he has no competing interests.

Acknowledgements

Dr Steven D. Wexner would like to gratefully acknowledge the contribution of Dr Stephen P. Sharp to the update for this topic. Dr Wexner would also like to acknowledge Dr Ahmed Sami Chadi, and Dr Paula I. Denoya, previous contributors to this topic.

Disclosures

SPS, ASC, and PID declare that they have no competing interests.

Peer reviewers

David J. Hackam, MD, PhD

Associate Professor of Pediatric Surgery

University of Pittsburgh School of Medicine

Pittsburgh

PA

Disclosures

DJH declares that he has no competing interests.

John Jenkins, MB CHB, FRCP

Consultant Colorectal Surgeon

St. Mark's Hospital

Harrow

UK

Disclosures

JJ declares that he has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Wattchow D, Heitmann P, Smolilo D, et al. Postoperative ileus- an ongoing conundrum. Neurogastroenterol Motil. 2021 May;33(5):e14046. Abstract

Gustafsson UO, Scott MJ, Hubner M, et al. Guidelines for perioperative care in elective colorectal surgery: Enhanced Recovery After Surgery (ERAS(®)) Society recommendations: 2018. World J Surg. 2019 Mar;43(3):659-95.Full text  Abstract

American College of Radiology. ACR appropriateness criteria: suspected small-bowel obstruction. 2019 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Ileus images
  • Differentials

    • Mechanical bowel obstruction
    • Pseudo-obstruction (Ogilvie syndrome)
    • Gastroenteritis
    More Differentials
  • Guidelines

    • ACR appropriateness criteria: suspected small-bowel obstruction
    • Guidelines for perioperative care in elective colorectal surgery
    More Guidelines
  • Videos

    Nasogastric tube insertion animated demonstration

    More videos
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