Alcohol withdrawal

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Evidence last reviewed: 18 Feb 2026
Topic last updated: 10 Dec 2024

Summary

Definition

History and exam

Key diagnostic factors

  • alcohol use
  • change in mental status
  • hallucinations
  • seizures
  • delusions
  • hypertension or hypotension
  • fever or hypothermia
  • hyperglycemia or hypoglycemia
  • features of clinical instability
Full details

Other diagnostic factors

  • tremor
  • nausea and vomiting
  • anorexia
  • anxiety/restlessness
  • emotional lability
  • insomnia
  • irritability
  • diaphoresis
  • headache
  • fine tremor
  • agitation
  • tachycardia
Full details

Risk factors

  • history of alcohol withdrawal syndrome (AWS) and alcohol withdrawal delirium
  • abrupt withdrawal of alcohol
Full details

Diagnostic tests

1st tests to order

  • BUN and serum creatinine
  • LFTs
  • ethanol concentration
  • electrolyte panel
  • CBC
Full details

Tests to consider

  • CT of head
  • chest x-ray
  • electroencephalogram (EEG)
  • blood-borne virus screen
Full details

Treatment algorithm

ACUTE

all patients

Contributors

Expert advisers

Hong K. Kim, MD, MPH

Associate Professor

Department of Emergency Medicine

University of Maryland School of Medicine

Baltimore

MD

Declarações

HKK declares that he has no competing interests.

Nicholas J. Connors, MD

Program Director

HCA Healthcare/Mercer University/Trident Medical Center

Emergency Medicine Residency Program

Charleston

SC

Declarações

NJC declares that he has no competing interests.

Revisores

Kinjal Sethuraman, MD, MPH

Associate Director

International Emergency Medicine

Long Island Jewish Hospital

New York

NY

Declarações

KS declares that he has no competing interests.

Paul S. Haber, MD

Royal Prince Alfred Hospital and Discipline of Medicine

The University of Sydney

Sydney

Australia

Declarações

PSH is an author of a reference cited in this topic.

Créditos aos pareceristas

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Referências

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Principais artigos

Bayard M, McIntyre J, Hill KR, et al. Alcohol withdrawal syndrome. Am Fam Physician. 2004 Mar 15;69(6):1443-50.Texto completo  Resumo

American Society of Addiction Medicine. The ASAM clinical practice guideline on alcohol withdrawal management. J Addict Med. 2020 May/Jun;14(3s suppl 1):1-72.Texto completo  Resumo

Bråthen G, Ben-Menachem E, Brodtkorb E, et al. Chapter 29: alcohol-related seizures. EFNS guidelines of alcohol-related seizures. In: Gilhus NE, Barnes MP, Brainin M, eds. European handbook of neurological management. 2nd ed, v1. Oxford, UK: Blackwell Publishing; 2011:429-36.

American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed. Text revision. (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.

Artigos de referência

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