Summary
Definition
Acute appendicitis is an acute inflammation of the vermiform appendix, most likely due to obstruction of the lumen of the appendix (by fecalith, normal stool, infective agents, or lymphoid hyperplasia).[1][2][Figure caption and citation for the preceding image starts]: Acute appendicitis - intraoperative specimen.Nasim Ahmed, MBBS, FACS; used with permission [Citation ends].
History and exam
Key diagnostic factors
- abdominal pain
- anorexia
- nausea and vomiting
- right lower quadrant tenderness
- tense rigid abdomen
- hypotension and tachycardia
- palpable mass
Other diagnostic factors
- age of occurrence
- fever
- flushed face and a fetor
- diminished bowel sounds
- tachycardia
- loose stool
- constipation
- Rovsing sign
- psoas sign
- obturator sign
Risk factors
- improved personal hygiene
- smoking
Diagnostic tests
1st tests to order
- CBC
- CRP
- abdominal and pelvic CT scan
Tests to consider
- abdominal ultrasound
- urinalysis
- urinary pregnancy test
- abdominal and pelvic MRI in pregnancy
Emerging tests
- Neutrophil-to-lymphocyte ratio
- serum sodium
- pentraxin-3
- serum amyloid A
- platelet indices
Treatment algorithm
uncomplicated acute appendicitis
ill with perforation or abscess
Contributors
Expert advisers
Forest W. Arnold, DO, MSc, FIDSA
Professor of Medicine
Chief, Division of Infectious Diseases
Director Infectious Diseases Fellowship Training Program
Department of Medicine
School of Medicine
University of Louisville
Louisville
KY
Disclosures
FWA declares that he has no competing interests.
Peer reviewers
Krishna Sundar, MD, FCCP
Associate Professor (Clinical)
Department of Medicine
University of Utah
Director
Pulmonary and Critical Care Research
IHC Urban South
Utah Valley Pulmonary Clinic
UT
Disclosures
KS declares that he has no competing interests.
Ozan Akca, MD
Director of Research
Associate Professor
Department of Anesthesiology and Perioperative Medicine
Neuroscience and Anesthesia Intensive Care Unit
University of Louisville
Louisville
KY
Disclosures
OA declares that he has no competing interests.
Differentials
- Acute mesenteric adenitis
- Viral gastroenteritis
- Meckel diverticulitis
More DifferentialsGuidelines
- Acute abdominal pain
- Clinical policy: critical issues in the evaluation and management of emergency department patients with suspected appendicitis
More GuidelinesCalculators
APACHE II scoring system
More CalculatorsVideos
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