Summary
Definition
History and exam
Key diagnostic factors
- localized pain in a dermatome
- pruritus
- rash
- corneal ulceration
Risk factors
- >50 years of age
- female sex
- HIV
- chronic corticosteroid use
- chemotherapy
- malignancies
- white ethnicity
Diagnostic investigations
Investigations to consider
- polymerase chain reaction (PCR)
- immunohistochemistry
- vesicular fluid culture
- HIV test
Treatment algorithm
Contributors
Authors
Assistant Professor
Center for Value-Based Care Research
Medicine Institute
Cleveland Clinic
Cleveland
OH
Disclosures
PL declares that she has no competing interests.
Professor
Center for Value-based Care Research
Medicine Institute
Cleveland Clinic
Cleveland
OH
Disclosures
MR received funds from Health Advances LLC for consulting on the role of cost-effectiveness in vaccine approval.
Dr Phuc Le and Dr Michael Rothberg would like to gratefully acknowledge Dr Kenneth J. Smith and Dr Linda Kalilani, the previous contributors to this topic.
Disclosures
KJS and LK declare that they have no competing interests.
Peer reviewers
Department of Epidemiology
Division of General Medicine and Epidemiology
UNC at Chapel Hill
Chapel Hill
NC
Disclosures
JA declares that he has no competing interests.
Consultant Virologist
Manchester Royal Infirmary
Manchester
UK
Disclosures
KM declares that he has no competing interests.
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