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Insomnia

Last reviewed: 27 Nov 2025
Last updated: 21 Oct 2025

Summary

Definition

History and exam

Key diagnostic factors

  • sleep partner complaints
  • delayed sleep onset
  • multiple or long awakenings
Full details

Other diagnostic factors

  • impairment of functioning
  • accidents
  • decreased sleep time
  • daytime napping
  • thyrotoxicosis
  • chronic pain
  • restless legs syndrome
  • obstructive sleep apnea
Full details

Risk factors

  • female sex
  • advanced age
  • chronic medical conditions
  • chronic pain
  • psychiatric illness
  • alcohol or substance misuse
  • stimulant use
  • poor sleep hygiene
  • traumatic brain injury
  • neuropsychiatric illness
  • use of certain medications
  • recent travel across time zones
  • night work
  • hyperthyroidism
  • participation in elite sport
  • sedentary behavior
Full details

Diagnostic tests

1st tests to order

  • sleep diary
  • Pittsburgh Sleep Quality Index (PSQI)
  • Insomnia Severity Index (ISI)
  • Stanford Sleepiness Scale (SSS)
  • Epworth Sleepiness Scale (ESS)
  • Athens Insomnia Scale (AIS)
  • Generalized Anxiety Disorder-7 (GAD-7)
  • Patient Health Questionnaire-9 (PHQ-9)
Full details

Tests to consider

  • polysomnography (PSG)
  • actigraphy
  • thyroid-stimulating hormone (TSH)
  • CBC and iron studies
  • urine or blood substance use panel
Full details

Treatment algorithm

ACUTE

acute insomnia

ONGOING

chronic insomnia

Contributors

Authors

Joshua Hyong-Jin Cho, MD, PhD

Health Sciences Clinical Professor

Director, UCLA Insomnia Clinic

Cousins Center for Psychoneuroimmunology

Department of Psychiatry & Biobehavioral Sciences

David Geffen School of Medicine at UCLA

Los Angeles

CA

Disclosures

JHC is an author of a reference cited in this topic.

Paul Barkopoulos, MD, MPH

Clinical Professor

Department of Psychiatry & Biobehavioral Sciences

David Geffen School of Medicine at UCLA

Los Angeles

CA

Disclosures

PB is an author of a reference cited in this topic.

Anthony E. Reading, MPhil, PhD

Clinical Professor

Department of Psychiatry & Biobehavioral Sciences

David Geffen School of Medicine at UCLA

Los Angeles

CA

Declarações

AER declares that he has no competing interests.

Agradecimentos

Dr Joshua Hyong-Jin Cho, Dr Paul Barkopoulos, and Dr Anthony E. Reading would like to gratefully acknowledge Dr John W. Winkelman, Dr Teofilo Lee-Chiong, and Dr Vipin Malik, previous contributors to this topic.

Declarações

JWW has received honoraria for consulting to Avadel, CVS, Eisai, and Merck, and research grants from Merck and the RLS Foundation. TLC is the Chief Medical Liaison for Philips, a company that makes devices to treat sleep apnea. VM received research funding from Philips Respironics for a study on COPD-OSA overlap.

Revisores

Karl Doghramji, MD

Director

Sleep Disorders Center

Thomas Jefferson University Hospital

Philadelphia

PA

Declarações

KD is a speaker for Sanofi-Aventis, King Pharmaceuticals, Takeda Pharmaceuticals, Sepracor, and Pfizer; a consultant for Sanofi-Aventis, Takeda Pharmaceuticals, Sepracor, Pfizer, and Neurocrine Biosciences; and has stock in Merck.

Chiadi U. Onyike, MD, MHS

Assistant Professor

Geriatric Psychiatry and Neuropsychiatry

The Johns Hopkins Hospital

Baltimore

MD

Declarações

CUO declares that he has no competing interests.

Roy Goldberg, MD

Medical Director

Kings Harbor Multicare Center

Bronx

NY

Declarações

RG declares that he has no competing interests.

Craig Sawchuk, MD

Affiliate Assistant Professor

Department of Psychiatry and Behavioral Sciences

University of Washington Medical Center

Seattle

WA

Declarações

CS declares that he has no competing interests.

David Cunnington, MD

Director

Melbourne Sleep Disorders Centre

Melbourne

Victoria

Australia

Declarações

DC has received consulting fees from Sanofi-Aventis and Lundbeck, and honoraria for speaking from Sanofi-Aventis.

Créditos aos pareceristas

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Referências

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Principais artigos

American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.Texto completo

Sateia MJ, Buysse DJ, Krystal AD, et al. Clinical practice guideline for the pharmacologic treatment of chronic insomnia in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2017 Feb 15;13(2):307-49.Texto completo  Resumo

Qaseem A, Kansagara D, Forciea MA, et al. Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2016 Jul 19;165(2):125-33.Texto completo  Resumo

Edinger JD, Arnedt JT, Bertisch SM, et al. Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2021 Feb 1;17(2):255-62.Texto completo  Resumo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
  • Diagnósticos diferenciais

    • Restless legs syndrome
    • Periodic limb movement disorder (PLMD)
    • Obstructive sleep apnea (OSA)
    Mais Diagnósticos diferenciais
  • Diretrizes

    • Manual for the scoring of sleep and associated events
    • Medicines associated with dependence or withdrawal symptoms: safe prescribing and withdrawal management for adults
    Mais Diretrizes
  • Folhetos informativos para os pacientes

    Insomnia

    Sleep apnea in adults (obstructive)

    Mais Folhetos informativos para os pacientes
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