Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- motor weakness
- loss of fine motor co-ordination
- spasticity
- paraesthesia, numbness, dysaesthesia
- hyperreflexia and ankle clonus
- pathological reflexes
- contractures
- loss of perianal sensation, voluntary anal contraction, and anal tone
- autonomic dysreflexia
- syrinx
Other diagnostic factors
- central (midline) pain
- girdle pain
- musculoskeletal or visceral pain
- unsteady gait
- urinary incontinence or retention
- constipation
- sexual dysfunction
- non-specific malaise
- radicular pain
Risk factors
- spinal cord trauma or ischaemia
- higher-level spinal cord lesion
- extremes of age
- narrow spinal canal
- male sex
Diagnostic investigations
Investigations to consider
- MRI spine
- EMG
- urodynamic studies
- bladder ultrasound
- renal ultrasound
- micturition cysto-urethrogram
- bone densitometry (DEXA)
- laboratory evaluation
Treatment algorithm
progressive neurological deficit
stable neurological status
Contributors
Authors
Cristina Sadowsky, MD
Clinical Director
International Center for Spinal Cord Injury
Kennedy Krieger Institute
Associate Professor Physical Medicine and Rehabilitation
Johns Hopkins School of Medicine
Baltimore
MD
Disclosures
CS is an author of a number of references cited in this topic.
Travis Edmiston, MD
Assistant Professor for Physical Medicine and Rehabilitation
International Center for Spinal Cord Injury
Kennedy Krieger Institute
Baltimore
MD
Disclosures
TE declares that he has no competing interests.
Acknowledgements
Dr Cristina Sadowsky and Dr Travis Edmiston would like to gratefully acknowledge Dr Kenneth Casey and Dr Jwalant Mehta, previous contributors to this topic.
Disclosures
KC and JM declare that they have no competing interests.
Peer reviewers
Steven Kirshblum, MD
Medical Director and Director of Spinal Cord Injury Services
Kessler Institute for Rehabilitation
West Orange
Professor
University of Medicine and Dentistry of New Jersey/New Jersey Medical School
Newark
NJ
Disclosures
SK declares that he has no competing interests.
Deborah Short, MRCP
Consultant in Rehabilitation Medicine
Robert Jones and Agnes Hunt Hospital
Oswestry
UK
Disclosures
DS declares that she has no competing interests.
Differentials
- Non-compressive myelopathy
- Compressive myelopathy
More DifferentialsGuidelines
- Best practice guidelines: spine injury
- CDC clinical practice guideline for prescribing opioids for pain: United States, 2022
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