Omphalocele and gastroschisis

Last reviewed: 20 Apr 2022
Last updated: 29 Apr 2022

Summary

Definition

History and exam

Key diagnostic factors

  • maternal age <20 years (gastroschisis)
  • maternal age >35 years (omphalocele)
  • elevated maternal serum alpha-fetoprotein (gastroschisis)
  • positive prenatal ultrasound
  • fetal chromosomal abnormalities (omphalocele)
  • abdominal contents external to the abdominal wall
More key diagnostic factors

Risk factors

  • maternal age <20 years (gastroschisis)
  • male sex of neonate (gastroschisis)
  • maternal age >35 years (omphalocele)
  • smoking
  • maternal infection during pregnancy
More risk factors

Diagnostic investigations

1st investigations to order

  • clinical diagnosis
More 1st investigations to order

Treatment algorithm

ACUTE

gastroschisis

omphalocele

Contributors

Authors

Cynthia L. Leaphart, BA, BS, MD
Cynthia L. Leaphart

Patient Safety

University of Florida College of Medicine

Jacksonville

FL

Disclosures

CLL declares that she has no competing interests.

Acknowledgements

Dr Cynthia L. Leaphart would like to gratefully acknowledge Dr Joseph T. Tepas, a previous contributor to this topic.

Disclosures

JTT declared that he had no competing interests.

Peer reviewers

Lewis Spitz, MBChB, PhD, FRCS, MD, FRCPCH, FAAP, FCS

Emeritus Nuffield Professor of Paediatric Surgery

Institute of Child Health

University College

London

UK

Disclosures

LS declares that he has no competing interests.

Fizan Abdullah, MD, PhD

Assistant Professor of Surgery

Division of Pediatric Surgery

Johns Hopkins University School of Medicine

Baltimore

MD

Disclosures

FA declares that he has no competing interests.

Ruth Hallows, BSc, MB BS, FRCS, FRCS III (Pediatric Surgery)

Consultant in Paediatric and Neonatal Surgery

Royal Alexandra Children's Hospital

Brighton

UK

Disclosures

RH declares that she has no competing interests.

Shilpi Chabra, MD

Assistant Professor

Department of Pediatrics

University of Washington Medical Center

Seattle

WA

Disclosures

SC declares that he has no competing interests.

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