Summary
Definition
History and exam
Other diagnostic factors
- sore throat
- neck lump
- indurated or ulcerated mass
- dysphagia
- neck lymphadenopathy
- otalgia
- trismus
- white plaques (leukoplakia) and red plaques (erythroplakia)
Diagnostic investigations
Investigations to consider
- CT scan of the head and neck
- MRI of the head and neck
- panendoscopy or triple endoscopy
- FNA of neck nodes
- excision biopsy of neck nodes
- modified barium swallow
- in situ hybridization for HPV-16, p16 immunohistochemistry, or PCR in biopsy specimen
- CBC
- electrolytes
- BUN
- serum creatinine
- total protein
- albumin
- prealbumin
- LFTs
Treatment algorithm
Contributors
Authors VIEW ALL
Professor and Chair
Radiation Oncology Department
Howard University
Washington
DC
Disclosures
NPN is an author of a number of references cited in this monograph.
Assistant Professor of Radiology
University of Arizona
Tucson
AZ
Disclosures
FA declares that he has no competing interests.
Dr Nam P. Nguyen and Dr Fabio Almeida would like to gratefully acknowledge Dr Linda Garland, a previous contributor to this monograph. LG is on the speakers' bureau for Sanofi-Aventis, maker of Taxotere.
Peer reviewers VIEW ALL
Chair
Multidisciplinary Head & Neck Team
Department of Head & Neck Oncology and Surgery
The Netherlands Cancer Institute
Amsterdam
The Netherlands
Disclosures
AJB declares that he has no competing interests.
Specializing in Head & Neck Cancer
Director of Clinical Trials
Radiation Oncology
H. Lee Moffitt Cancer Center & Research Institute
Tampa
FL
Disclosures
AT is an author of a reference cited in this monograph.
Assistant Professor of Medicine
Yale Cancer Center
Yale University
New Haven
CT
Disclosures
HD is on the speakers' bureau for Sanofi-Aventis and has received reimbursement for talks given about their product Taxotere.
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