Last reviewed: 7 Feb 2021
Last updated: 13 Aug 2019
Summary
Definition
History and exam
Key diagnostic factors
- acute to subacute recurrent skin eruption
- polymorphic, generalized, nonpruritic skin eruption
Other diagnostic factors
- scars or pigment changes
- immunosuppression
- recent illness
- family history of pityriasis lichenoides
- headache
- myalgias/arthralgias
- malaise
- burning/pruritus
- multiorgan failure
Diagnostic investigations
Investigations to consider
- antistreptolysin titers
- Epstein-Barr virus IgM/IgG viral capsid antigen and nuclear antigen antibody
- monospot or heterophil antibody test
- hepatitis B surface antigen, antisurface antibody, and anticore IgM
- hepatitis C virus antibody
- HIV screening
- rapid plasma reagin
- throat cultures
- toxoplasma Sabin-Feldman dye test, indirect immunofluorescence/hemagglutination
- erythrocyte sedimentation rate
- CRP
- serum LDH
- WBC count
- serum albumin
Treatment algorithm
Contributors
Authors
Clinical Instructor in Dermatology
SUNY Downstate Medical Center
Brooklyn
NY
Disclosures
AK declares that he has no competing interests.
Dermatology Faculty
Department of Dermatology & Cutaneous Surgery
University of Miami
Miami
FL
Disclosures
MB-K declares that she has no competing interests.
Peer reviewers
Resident
Department of Dermatology
Wake Forest University School of Medicine
Winston-Salem
NC
Disclosures
ADL declares that he has no competing interests.
Assistant Professor
King Fahd University of Petroleum and Minerals
Dhahran
Saudi Arabia
Disclosures
AS declares that he has no competing interests.
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