Summary
Definition
History and exam
Key diagnostic factors
- repeated attacks of unilateral pain
- excruciating pain
- lacrimation, rhinorrhea, and partial Horner syndrome
- agitation
- nausea, vomiting
- photophobia, phonophobia
- migrainous aura
Diagnostic investigations
1st investigations to order
- brain CT scan or MRI
- erythrocyte sedimentation rate
- pituitary function tests
Treatment algorithm
Contributors
Authors
Clinical Research Fellow
Headache Group
National Hospital for Neurology and Neurosurgery
London
UK
Disclosures
SM declares that she has received an educational grant from St Jude Medical and Medtronic. SM has received payment for educational presentations from Allergan and Autonomic Technologies, Inc.
Consultant Neurologist
Southern General Hospital
Glasgow
UK
Disclosures
AT has been on advisory boards for Allergan and electroCore. AT has received organisational payments from eNeura, Allergan, and electroCore.
Senior Lecturer and Honorary Consultant Neurologist
Headache Group
National Hospital for Neurology and Neurosurgery
London
UK
Disclosures
MSM serves on the advisory board for Allergan, St Jude Medical, and Medtronic. MSM has received payment for the development of educational presentations from Allergan, MSD, Medtronic, and electroCore.
Dr Sarah Miller, Dr Alok Tyagi, and Dr Manjit S. Matharu would like to gratefully acknowledge the assistance of Dr Marc S. Husid and Dr Davis L. Mellick. MSH and DLM declare that they have no competing interests.
Peer reviewers
Director of Headache and Pain Medicine
Professor of Neurology, Anesthesiology, and Rehabilitation Medicine
Icahn School of Medicine at Mount Sinai
New York
NY
Disclosures
MWG declares that he has no competing interests.
Professor
Family and Community Medicine
University of Kansas School of Medicine
Wichita
KS
Disclosures
AW declares that she has no competing interests.
Department Head
Department of Neurology and Pain Medicine
Konventhospital Barmherzige Brüder Linz
Linz
Austria
Disclosures
CL declares that he has no competing interests.
Use of this content is subject to our disclaimer