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Cluster headache

Last reviewed: 11 Jun 2025
Last updated: 02 Apr 2025

Summary

Definition

Анамнез и осмотр

Ключевые диагностические факторы

  • repeated attacks of unilateral pain
  • short duration
  • excruciating pain
  • lacrimation, rhinorrhea, and partial Horner syndrome
  • agitation and restlessness
Полная информация

Факторы риска

  • male sex
  • family history
  • head injury
  • cigarette smoking
  • heavy drinking
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • brain and pituitary MRI without and with intravenous contrast
  • erythrocyte sedimentation rate
Полная информация

Tests to avoid

  • Electroencephalography (EEG)
Полная информация

Исследования, проведение которых нужно рассмотреть

  • pituitary function tests
  • magnetic resonance angiography (MRA) head and neck with and without contrast
  • brain CT scan
  • polysomnogram
  • ECG
Полная информация

Алгоритм лечения

Острый

acute attack: without cardiovascular disease, cerebrovascular disease, or uncontrolled hypertension

acute attack: with cardiovascular disease, cerebrovascular disease, or uncontrolled hypertension

ПРОДОЛЖЕНИЕ

preventive treatment for episodic cluster headache

preventive treatment for chronic cluster headache

Составители

Авторы

Juliana VanderPluym, MD, FRCPC, FAHS

Associate Professor of Neurology

Department of Neurology

Mayo Clinic Arizona

Scottsdale

AZ

Раскрытие информации

JVP has received a research grant from Amgen. She has previously acted as a consultant for Teva and is on the editorial board of the American Migraine Foundation. JVP is a co-editor of the Headache section for Current Neurology and Neuroscience Reports.

Amaal J. Starling, MD

Associate Professor of Neurology

Department of Neurology

Mayo Clinic Arizona

Scottsdale

AZ

Раскрытие информации

AJS serves on the Board of Directors for the American Headache Society, the Alliance for Headache Disorders Advocacy, and the United Council for Neurologic Subspecialties. AJS has received consulting fees from AbbVie, Allergan, Amgen, Axsome Therapeutics, Eli Lilly & Company, Everyday Health, Impel, Lundbeck, Med-IQ, Medscape, Neurolief, Novartis, Satsuma, Teva, and Theranica. None are directly related to the topic of cluster headache.

Christoper C. Anderson, MD

Headache Medicine Fellow Physician

Mayo Clinic Arizona

Scottsdale

AZ

Раскрытие информации

CCA declares that he has no competing interests.

Выражение благодарностей

Dr Juliana VanderPluym, Dr Amaal J. Starling, and Dr Christopher C. Anderson would like to gratefully acknowledge Dr Sarah Miller, Dr Alok Tyagi, Dr Manjit S. Matharu, Dr Marc S. Husid, and Dr Davis L. Mellick, previous contributors to this topic.

Раскрытие информации

SM received an educational grant from St Jude Medical and Medtronic, and received payment for educational presentations from Allergan and Autonomic Technologies, Inc. AT was on advisory boards for Allergan and electroCore, and received organizational payments from eNeura, Allergan, and electroCore. MSM served on the advisory board for Allergan, St Jude Medical, and Medtronic, and received payment for the development of educational presentations from Allergan, MSD, Medtronic, and electroCore. MSH and DLM declare that they have no competing interests.

Рецензенты

Mark W. Green, MD, FAAN

Director of Headache and Pain Medicine

Professor of Neurology, Anesthesiology, and Rehabilitation Medicine

Icahn School of Medicine at Mount Sinai

New York

NY

Раскрытие информации

MWG declares that he has no competing interests.

Anne Walling, MD

Professor

Family and Community Medicine

University of Kansas School of Medicine

Wichita

KS

Раскрытие информации

AW declares that she has no competing interests.

Christian Lampl, MD, PhD

Department Head

Department of Neurology and Pain Medicine

Konventhospital Barmherzige Brüder Linz

Linz

Austria

Раскрытие информации

CL declares that he has no competing interests.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

Schindler EAD, Burish MJ. Recent advances in the diagnosis and management of cluster headache. BMJ. 2022 Mar 16;376:e059577. Аннотация

Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018 Jan;38(1):1-211.Полный текст  Аннотация

American College of Radiology. ACR appropriateness criteria: headache. 2022 [internet publication].Полный текст

Robbins MS, Starling AJ, Pringsheim TM, et al. Treatment of cluster headache: the American Headache Society evidence-based guidelines. Headache. 2016 Jul;56(7):1093-106.Полный текст  Аннотация

Law S, Derry S, Moore RA. Triptans for acute cluster headache. Cochrane Database Syst Rev. 2013 Jul 17;(7):CD008042.Полный текст  Аннотация

May A, Evers S, Goadsby PJ, et al. European Academy of Neurology guidelines on the treatment of cluster headache. Eur J Neurol. 2023 Oct;30(10):2955-79.Полный текст  Аннотация

Статьи, указанные как источники

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