Last reviewed: 1 Feb 2021
Last updated: 09 Jul 2019
Summary
Definition
History and exam
Key diagnostic factors
- recreational or occupational exposures
- primary residence in or travel to endemic areas
Other diagnostic factors
- male sex
- age 30 to 50 years
- constitutional symptoms
- cough
- skin lesions
- animal exposure
- bone or joint pain
- genitourinary symptoms
- headache or focal neurologic complaints
Risk factors
- male sex
- recreational or occupational exposures
- travel to or residence in an area of endemicity
- immunocompromise
Diagnostic investigations
Investigations to consider
- bronchoscopy
- tissue biopsy or cytology (lung, skin, or bone)
- arthrocentesis
- fungal serology panel
- Blastomyces dermatitidis antigen testing (urine, bronchoalveolar lavage, or serum)
- fungal blood cultures
- MRI brain
- B dermatitidis polymerase chain reaction
Treatment algorithm
Contributors
Authors
Assistant Professor of Medicine
Division of Infectious Diseases
Mayo Clinic
Rochester
MN
Disclosures
NC declares that he has no competing interests.
Professor Emeritus of Medicine
Division of Infectious Diseases
Mayo Clinic
Rochester
MN
Disclosures
LB declares that he has no competing interests.
Peer reviewers
Assistant Professor of Medicine
Department of Medicine
Section of Pulmonary and Critical Care
University of Chicago
Chicago
IL
Disclosures
KH declares that he has no competing interests.
Associate Professor of Medicine
Stanford University
Stanford
Staff Physician
US Department of Veterans Affairs
Palo Alto Health Care System
Palo Alto
CA
Disclosures
WK declares that he has no competing interests.
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