Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- postural and/or kinetic tremor
- problems with fine motor tasks
Other diagnostic factors
- abatement of tremor after consumption of alcohol, benzodiazepines, barbiturates, or gabapentin
- head or voice tremor
- resting tremor
Risk factors
- advanced age
- family history
- white ancestry
- exposure to environmental toxins
Diagnostic investigations
1st investigations to order
- clinical diagnosis
Investigations to consider
- CT or MRI scan of the head
- serum ceruloplasmin
- 24-hour urine copper
- thyroid function tests
- tremor physiology studies
- single-photon emission CT (SPECT) scan of the head
Emerging tests
- tremor stability index
Treatment algorithm
no dysfunction or embarrassment
dysfunction or embarrassment
Contributors
Authors
Sheng-Han Kuo, MD
Assistant Professor of Neurology
College of Physicians and Surgeons
Columbia University
New York
NY
Disclosures
S-HK is an author of a number of references cited in this topic.
Ming-Kai Pan, MD, PhD
Assistant Professor of Neurology
College of Medicine
National Taiwan University
Tapei
Taiwan
Disclosures
M-KP has been a member of the Tremor Study Group and the International Parkinson and Movement Disorder Society.
Acknowledgements
Dr Sheng-Han Kuo and Dr Ming-Kai Pan would like to gratefully acknowledge Dr Zoltan Mari, Dr Martin Kronenbuerger, Dr Adam Burdick, and Dr Kelly D. Foote, previous contributors to this topic.
Disclosures
ZM has directed various educational programmes, accredited (CME) by Johns Hopkins University, and has accepted honoraria for consulting. MK, AB, and KDF declare that they have no competing interests.
Peer reviewers
Roger Weis, MD
Pediatric Neurologist
Kinderneurologisches Zentrum Mainz
Mainz
Germany
Disclosures
RW declares that he has no competing interests.
Cory Toth, BSc, MD, FRCP(C)
Assistant Professor of Neurosciences
Hotchkiss Brain Institute
University of Calgary
Alberta
Canada
Disclosures
CT declares that he has no competing interests.
Differentials
- Parkinson's disease
- Dystonia
- Wilson's disease
More DifferentialsGuidelines
- Suspected neurological conditions: recognition and referral
- American Society for Stereotactic and Functional Neurosurgery position statement on magnetic resonance-guided focused ultrasound for the management of essential tremor
More GuidelinesPatient information
Essential tremor
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